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妊娠期恶性肿瘤四例临床分析及文献复习 被引量:5

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摘要 目的探讨妊娠期肺癌和结直肠癌的诊治及预后。方法回顾性分析首都医科大学附属北京友谊医院收治的3例妊娠期肺癌、1例妊娠期结直肠癌(乙状结肠癌)患者的临床病理资料,并进行相关文献复习。结果3例妊娠期肺癌患者,其年龄均<40岁;诊断孕周分别为20、22和36周;主要临床表现为咳血1例,咳嗽、咳痰伴左胸及左背部疼痛1例,可扪及颈部转移性包块1例;2例行胸片检查者分别提示左肺高密度块状影及大量胸腔积液,3例行CT检查者表现为肺不张、支气管截断、胸腔积液及肺门旁不规则软组织影;临床分期为Ⅲ期1例,Ⅳ期2例;病理类型为肺腺癌1例,肺小细胞神经内分泌癌1例,肺腺癌合并神经内分泌癌1例;2例孕中期诊断肺癌后行中期引产术,术后转外院治疗肺癌,分别于中期引产术后的4、7个月死亡,另1例患者孕36周诊断,孕37周剖宫产术后予放化疗,产后随访12个月无复发。1例妊娠期结直肠癌患者,36岁,孕38周起出现左上腹痛伴便秘,无恶心、呕吐等,影像学检查提示乙状结肠恶性肿瘤(结肠癌可能性大),肝多发转移瘤,大网膜种植转移,伴腹腔多发肿大淋巴结;剖宫产术后8 d出现大量便血,急诊予肠系膜下动脉持续垂体后叶素泵入止血治疗,病情稳定后转入外科行乙状结肠广泛性切除+降结肠单腔造瘘术;手术病理分期为Duck D期,术后未行放化疗,术后32 d死亡。结论妊娠期肺癌和结直肠癌临床少见,对妊娠期反复出现呼吸道症状者,应警惕妊娠期肺癌及时行影像学检查,必要时取活检,争取早期诊断;妊娠期结直肠癌的临床表现不特异,诊断和治疗均十分棘手,患者发现时常常已是晚期。妊娠期肺癌和结直肠癌患者属高危妊娠,总体预后差。
作者 韩肖燕 杨桦
出处 《中华妇产科杂志》 CAS CSCD 北大核心 2019年第7期480-484,共5页 Chinese Journal of Obstetrics and Gynecology
作者简介 通信作者:杨桦,Email:yanghuawst@163.com.
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  • 1Hermann Brenner,Michael Hoffmeister,Christa Stegmaier,Gerhard Brenner,Lutz Altenhofen,Ulrike Haug.Risk of progression of advanced adenomas to colorectal cancer by age and sex: estimates based on 840 149 screening colonoscopies. Gut . 2007
  • 2Evangelos D.Lolis,PaulosLikoudis,PanagiotisVoiniadis,DimitriosHassiakos,LazarosSamanides.??Synchronous rectal and colon cancer caused by familial polyposis coli during pregnancy(J)Journal of Obstetrics and Gynaecology Research . 2007 (2)
  • 3Hatem A. Azim,Fedro A. Peccatori,Nicholas Pavlidis.??Treatment of the pregnant mother with cancer: A systematic review on the use of cytotoxic, endocrine, targeted agents and immunotherapy during pregnancy. Part I: Solid tumors(J)Cancer Treatment Reviews . 2009 (2)
  • 4Page I. Wang,Suzanne T. Chong,Ania Z. Kielar.Imaging of Pregnant and Lactating Patients: Part 1, Evidence-Based Review and Recommendations. American Journal of Roentgenology . 2012
  • 5Patrick S. Tawadros,Ian M. Paquette,Ann M. Hanly,Anders F. Mellgren,David A. Rothenberger,Robert D. Madoff.??Adenocarcinoma of the Rectum in Patients Under Age 40 Is Increasing: Impact of Signet-Ring Cell Histology(J)Diseases of the Colon & Rectum . 2015 (5)
  • 6Ciaran Walsh,Victor W. Fazio.??CANCER OF THE COLON, RECTUM, AND ANUS DURING PREGNANCY(J)Gastroenterology Clinics of North America . 1998 (1)
  • 7M. A. Bernstein,R. D. Madoff,P. F. Caushaj.??Colon and rectal cancer in pregnancy(J)Diseases of the Colon & Rectum . 1993 (2)
  • 8Erman Aytac,Gokhan Ozuner,Ozgen Isik,Emre Gorgun,Feza H. Remzi.Surgical management of patients with ulcerative colitis during pregnancy:Maternal and fetal outcomes. J Crohns Colitis . 2015
  • 9Litton JK,Hodge S,Mattair D,Ramirez MM,Morrow PKH,Gonzalez-Angulo AM,Barnett CM,Hortobagyi GN,Theriault RL.Outcomes of children exposed to chemotherapy in utero for breast cancer. Journal of Clinical Oncology . 2011
  • 10Humphrey G.M. Walker,Ahmad Al Samaraee,Sarah J. Mills,M. Reza Kalbassi.??Laparoscopic appendicectomy in pregnancy: A systematic review of the published evidence(J)International Journal of Surgery . 2014

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