摘要
目的通过对中医时间医学中胸痹心痛相关古籍文献的整理分析,研究古籍文献中胸痹心痛择时服药内容。方法依托《中华医典》数据库检索古籍条文,建立数据库,对涵盖服药时间的胸痹心痛方剂进行内容提取,针对择时服药进行统计分析和内容探讨。结果所纳入的67种中药类别为理气剂、祛寒剂、祛痰剂和理血剂;择时服药时间点主要为寅时(3:00-5:00),辰时(7:00-9:00),午时(11:00-13:00),酉时(17:00-19:00),戌时(19:00-21:00),亥时(21:00-23:00);服药频次以平旦服、日二服、日三服、日三夜一服为主。推荐临床择时服药增加平旦寅时空心服和亥时临卧服,注重心经旺时日中午时和心包经旺时戌时择时服药。结论择时服药有益于中药疗效最优化和药物毒性最低化,有待进一步多中心临床试验研究提供最佳证据,推动择时服药在临床实践推广。
Objective Based on the analysis of the ancient literatures about chest stuffiness and pains in Chrono-Medicine of traditional Chinese medicine,to study the content of timing medication in chest stuffiness and pains. Methods According to the database of Chinese Medical Code, searching the ancient literatures and establishing the database, extracting the contents of chest stuffiness and pains’s prescription which covering timing medication. And the statistical analysis and content discussion were carried out according to the choice of taking medicine. Results The 67 kinds of traditional Chinese medicine included were qi regulating agent, dispelling cold agent, expectorant agent and blood regulating agent. Besides,the time of taking medicine is used to be3:00-5:00,7:00-9:00,11:00-13:00,17:00-19:00, 19:00-21:00, 21:00-23:00.Take medicine once a day in the morning, twice a day, three times a day, three times a day and once a night. It is recommended that timing medication in clinical should be increased in time of 21:00-23:00 and 11:00-13:00, and paying more attention to the heart channel corresponding and the heart pericardium channel in time of 11:00-13:00 and 19:00-21:00. Conclusion Timing medication is beneficial to the optimization of therapeutic effect and minimization of toxicity of traditional Chinese medicine, which needs to provide the best evidence for further multi-center clinical trial research, and promote the popularization of timing medicine in clinical practice.
作者
丁慧鑫
于春光
张春花
王玲
李佩瑶
Ding Huixin;Yu Chunguang;Zhang Chunhua;Wang Ling;Li Peiyao(School of Nursing, Beijing University of Chinese Medicine, Beijing 100029, China)
出处
《中国实用护理杂志》
2019年第20期1576-1581,共6页
Chinese Journal of Practical Nursing
关键词
中医时间医学
胸痹心痛
择时服药
古籍
Chrono-Medicine (Traditional Chinese Medicine)
Chest stuffiness and pains
Timing Medication
Ancient literature
作者简介
通信作者:于春光,Email:bjchunguang@163.com,电话:13911187432.
