摘要
目的评价射频消融与冷冻消融治疗晚期非小细胞肺癌的局部疗效,探讨两种治疗方案的价值。方法筛选30例有消融治疗适应证的晚期(ⅢB~Ⅳ期)非小细胞肺癌患者,随机分配至射频消融组及冷冻消融组,每组15例。分别进行射频消融或冷冻消融治疗,术后7天、1个月、3个月分别行MR弥散功能成像对患者的局部疗效进行评价。结果两种治疗方案在术后7天、1个月、3个月行MR弥散功能成像,局部疗效的差异无统计学意义(P> 0. 05),但并发症率的差异有统计学意义(P <0. 05)。结论射频消融与冷冻消融在治疗非小细胞肺癌的局部疗效上无明显差异,但冷冻消融的并发症率更低,更值得临床推广。
Objective To evaluate the local therapeutic efficacy of non-small cell lung cancer with radiofrequency ablation( RFA) and cryoablation with MR diffusion weighted imaging( DWI) to explore the value of two treatments. Methods Thirty patients with advanced( IIIB-IV) non-small cell lung cancer who had indications for ablation were randomly assigned to the radiofrequency ablation group and cryoablation group,with 15 patients in each group. Radiofrequency ablation or cryoablation was performed separately. MR diffusion function imaging was performed at 7 days,1 month,and 3 months after surgery to evaluate the local efficacy of the patients. Results MR diffusion imaging was performed at 7 days,1 month,and 3 months after operation. There was no significant difference in local efficacy( P > 0. 05),but the difference in complication rate was statistically significant( P < 0. 05). Conclusion There was no significant difference in local therapeutic efficacy between two groups,but the complication rate of cryoablation was lower and worth opularizing application in clinic.
作者
蔡越飞
冼重杨
简燕
朱刚明
CAI Yuefei;XIAN Chongyang;JIAN Yan;ZHU Gangming(Dongguan Donghua Hospital, Dongguan 523110, China)
出处
《现代医院》
2019年第6期895-898,共4页
Modern Hospitals
