摘要
以壳寡糖、2,4-二氯苯氧乙酸为原料,经壳寡糖氨基保护、2,4-二氯苯氧乙酸的羧基酰氯化、酰氯化后的2,4-二氯苯氧乙酸与壳寡糖羟基反应、脱除壳寡糖氨基保护最终得到2,4-二氯苯氧乙酸壳寡糖酯(Dcpo- O -COS)。通过傅里叶红外、紫外可见吸收、 1 H核磁共振对2,4-二氯苯氧乙酸壳寡糖酯进行了结构表征,证明成功合成终产物。经X射线衍射仪、热分析仪、抗菌性研究测定,终产物的热稳定性、对大肠杆菌及金黄色葡萄球菌的抗菌性较原料壳寡糖有所提高。
The O -2,4-dichlorophenoxyacetic-oligochitosan (Dcpo-O-COS) was synthesized by chitosan oligosaccharide (COS) and 2,4-dichlorophenoxyacetic acid. The steps were as followed: amino protecting of chitosan oligosaccharide, carboxyl acyl chlorination of 2,4-dichlorophenoxyacetic acid, hydroxyl of COS reacted with acyl chlorination 2,4-dichlorophenoxyacetic acid, amino deprotection. Fourier transform infrared (FTIR), UV-Vis absorption and 1 H nuclear magnetic resonance (NMR) were used to characterize the structure of the final product. The results exhibited that Dcpo-O-COS was successfully synthesized. Moreover, both stability, tested by X-ray diffraction (XRD) and Thermogravimetric Analysis (TGA), and antibacterial activity, toresistance to Escherichia coli and Staphylococcus aureus, of Dcpo- O -COS were higher than COS.
作者
袁晓娴
乐琳
姜启兴
刘晓丽
陈琬雯
夏文水
平原
YUAN Xiao-xian;YUE Lin;JIANG Qi-xing;LIU Xiao-li;CHEN Wan-wen;XIA Wen-shui;PING Yuan(School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China;Synergetic Innovation Center of Food Safety and Quality Control, Jiangsu Province, Wuxi, Jiangsu 214122, China;Suzhou Fengbei Biotech Co., Ltd., Suzhou, Jiangsu 215000, China)
出处
《食品与机械》
北大核心
2019年第6期74-78,99,共6页
Food and Machinery
关键词
2
4-二氯苯氧乙酸壳寡糖酯
壳寡糖
2
4-二氯苯氧乙酸
合成
抗菌性
O-2,4-dichlorophenoxyacetic-oligochitosan
chitosan
2,4-dichlorophenoxyacetic acid
synthesis
antibacterial activity
作者简介
袁晓娴,女,江南大学在读硕士研究生;通信作者:乐琳(1973-),男,江南大学副教授,博士。E-mail:yuelin@jiangnan.edu.cn.
