摘要
目的探究多囊卵巢综合征患者接受达英-35与二甲双胍联合治疗的价值。方法以多囊卵巢综合征患者为研究对象,例数为100例,时间为2016年1月—2018年1月,采用分段随机化法分组,其中对照组实施达英-35治疗,试验组则实施达英-35与二甲双胍联合治疗,分析2组多囊卵巢综合征患者治疗的结果。结果两组治疗后的睾酮、黄体生成素、基础卵泡刺激素、催乳素水平均较治疗前显著改善,其中试验组治疗后的睾酮、黄体生成素水平明显优于对照组(P <0.05);试验组的排卵率明显高于对照组,差异具有统计学意义(P <0.05)。结论相比达英-35单药治疗,多囊卵巢综合征患者接受达英-35与二甲双胍联合治疗,可更有效降低睾酮和黄体生成素水平。
Objective To explore the value of polycystic ovary syndrome (PCOS) patients receiving combination therapy of ethinylestradiol and metformin. Methods In patients with polycystic ovary syndrome as the research object, the number of cases of 100 cases, from January 2016 to January 2018, grouped by segmentation randomized method, including the control implementation ethinylestradiol cyproterone treatment, the experimental group was implemented ethinylestradiol and cyproterone metformin combination therapy, and analyzed the results of two groups treatment in patients with polycystic ovary syndrome. Results The levels of testosterone, luteinizing hormone, basal follicle stimulating hormone and prolactin in the two groups were significantly improved compared with those before treatment. The testosterone and luteinizing hormone levels in the experimental group were significantly better than those in the control group (P < 0.05). The ovulation rate of the experimental group was significantly higher than that of the control group, and the difference was statistically significant (P < 0.05). Conclusion Compared with ethinyl estradiol cyproterone tablets alone, patients with polycystic ovary syndrome receive ethinyl estradiol cyproterone tablets in combination with metformin, which can reduce testosterone and luteinizing hormone levels more effectively.
作者
李慧
潘林清
唐淮云
贾洪燕
关慧娟
LI Hui;PAN Linqing;TANG Huaiyun;JIA Hongyan;GUAN Huijuan(Department of Reproductive Medicine,Lianyungang Maternal and ChildHealth Hospital,Jiangsu Province,Lianyungang Jiangsu 222000,China)
出处
《中国卫生标准管理》
2019年第9期91-93,共3页
China Health Standard Management
关键词
达英-35
PCOS
排卵
二甲双胍
睾酮
黄体生成素
基础卵泡刺激素
催乳素
ethinyl estradiol
Polycystic ovary syndrome
ovulation
metformin
Testosterone
luteinizing hormone
basic follicle stimulating hormone
prolactinc
