摘要
目的:从生产/流通企业角度了解四川省医疗机构药品短缺的原因并提出相应对策,为建立药品短缺供应保障机制提供参考。方法:采用问卷调查的方式对该省78家医疗机构2015年1月-2017年6月期间的药品短缺情况进行调查;对短缺药品涉及的生产企业和流通企业进行溯源调查,综合问卷调查及实地调研,了解该省出现药品短缺的原因,并提出应对措施。结果:本次调研共向医疗机构发放78份调查问卷,回收率、有效率均为100%;78家医疗机构共上报了206种药品,共计240个品规出现短缺。向短缺药品涉及的生产企业和流通企业分别发放140、68份调查问卷,回收率和有效率均为100%;结合现场实地调研,共获得212个品规的短缺药品调研结果。从生产企业角度出发,造成药品短缺的最主要因素是生产性成本上涨(占66.51%)和流通成本上涨(占26.88%);从药品流通企业角度出发,造成药品短缺的最主要因素是货源供应不足或缺货(占75.47%)、库存管理问题(占16.51%)和价格倒挂(占11.32%)。结论:导致药品短缺的生产/流通企业方原因主要包括生产性成本和流通成本的提高、药品价格倒挂、库存管理及招标采购问题。建议通过完善药品招标定价制度、调动企业积极性,完善企业短缺药品预警机制、加强信息沟通,建立短缺药品储备机制、组织短缺药品的应急生产,加强短缺药品供应链管理、净化市场不良风气,完善短缺药品紧急处置办法、提高短缺药品的供应保障能力等措施,多部门协同合作,减少药品短缺现象的出现,保障临床持续获得安全、有效的药品。
OBJECTIVE:To investigate the reasons for drug shortage in medical institutions of Sichuan province and put forward relevant countermeasures,and to provide reference for establishing supply security mechanism of drug shortage.METHODS:Questionnaire survey was conducted to investigate drug shortage in 78 medical institutions of the province during Jan.2015-Jun.2017.Traceability investigation was conducted from manufacturers and distribution enterprises involved in drug shortage.Questionnaire survey and field investigation were combined to analyze the reasons for drug shortage in Sichuan province and put forward countermeasures.RESULTS:Totally 78 questionnaires were sent out to medical institutions with recovery rate and effective rate of 100%.A total of 206 drugs were reported by 78 medical institutions,involving 240 specifications for shortage in total.Totally 140 questionnaires and 68 questionnaires were distributed to the manufacturers and distribution enterprises involved in drug shortage,and the recovery rate and effective rate were all 100%.Combined with the field survey,survey results of shortage drugs of 212 specifications were obtained.From the perspective of manufacturers,the most important factors causing drug shortage were the increase of production cost(66.51%)and circulation cost(26.88%).From the perspective of distribution enterprises,the main factors causing drug shortage were insufficient supply of drugs(75.47%),inventory management(16.51%)and price inversion(11.32%).CONCLUSIONS:Main reasons of drug shortage from manufacturers and distribution enterprises include the increase of production cost and circulation cost,drug price inversion,inventory management and bidding procurement.It is suggested that measures should be taken to improve the bidding and pricing system of drugs,mobilize the enthusiasm of enterprises;improve the early warning mechanism of drug shortage on the enterprises,strengthen information communication;establish the mechanism of drug shortage reserve,organize the emergency production of drug for shortage;strengthen the management of drug shortage supply chain,purify the unhealthy atmosphere in the market;improve the emergency disposal methods of drug shortage,and improve the supply guarantee ability of drug shortage.Departments cooperate to reduce the emergence of drug shortage and ensure the continuous access to safe and effective drugs in clinic.
作者
闫峻峰
吴姗
于楠
任智文
罗维楠
朱昶宇
武航海
YAN Junfeng;WU Shan;YU Nan;REN Zhiwen;LUO Weinan;ZHU Changyu;WU Hanghai(Sichuan Academy of Medical Sciences/Sichuan Provincial People’s Hospital/the Affiliated Hospital of University of Electronic Science and Technology of China/Individualized Drug Treatment Key Laboratory of Sichuan Province,Chengdu 610072,China;School of Medicine,University of Electronic Science and Technology of China,Chengdu 610054,China;Dept.of Pharmacy,Maternal and Child Health Hospital of Shuangliu District of Chengdu,Chengdu 610200,China)
出处
《中国药房》
CAS
北大核心
2019年第10期1307-1311,共5页
China Pharmacy
基金
国家卫生计生委药政司委托研究课题(No.药政﹝2016﹞45号)
四川省科研院所成果转化项目(No.2017YSZH0028)
关键词
药品短缺
药品供应
生产企业
流通企业
原因
对策
Drug shortage
Drug supply
Manufacturers
Distribution enterprises
Reasons
Countermeasures
作者简介
闫峻峰,主任药师,硕士生导师。研究方向:国家药物政策、药事管理、医院药学。电话:028-87393436。E-mail:289302309@qq.com.
