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羟考酮用于老年腹腔镜胆囊切除术患者的临床观察 被引量:3

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摘要 目的观察羟考酮用于老年腹腔镜胆囊切除术患者的临床效果。方法选择2018年1月至2018年12月在我院全身麻醉下行腹腔镜下胆囊切除术患者120例,年龄65-75岁,ASA分级Ⅰ-Ⅲ级,随机分为2组,羟考酮组(O组)和对照组(C组),每组60例。两组患者均行喉罩插管全身麻醉,在成功建立人工气腹后,O组静脉注射羟考酮0.07mg/kg,C组静脉注射等容量盐水。分别于麻醉诱导前(T_0)、插入喉罩后5min(T_1)、切皮时(T_2)及牵拉腹腔脏器时(T_3)记录患者的血压、心率、镇痛/伤害性刺激指数(ANI)及末梢灌注指数(PI),并记录患者术后肩背部疼痛及恶心呕吐的发生情况。结果两组患者在T_0、T_1、T_23个时点的血压及心率无明显差异(P>0.05);在T_3时点C组患者血压、心率明显高于O组(P<0.05);C组在T_3时ANI和PI值明显低于T_1(P<0.05);C组术后肩背部疼痛及术后恶心呕吐发生率均较O组明显升高(P<0.05)。结论羟考酮可减轻老年腹腔镜胆囊切除术患者由于牵拉腹腔脏器引发的交感神经张力增高,并可明显减轻由于胆囊切除后引发的肩背部疼痛,降低术后恶心呕吐的发生率。
作者 罗晓东
出处 《江西医药》 CAS 2019年第3期272-274,共3页 Jiangxi Medical Journal
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