摘要
目的探讨冠心病心力衰竭患者在美托洛尔给药基础上,加用银杏叶片效果及预后。方法选择我院心血管内科2017年3月—2018年3月收治冠心病心力衰竭患者80例作为研究对象。将其随机分为两组。对照组(n=40)患者单用美托洛尔治疗,观察组(n=40)患者在美托洛尔给药基础上,联用银杏叶片治疗。比较两组患者的治疗总有效率、心功能、相关血清因子水平。结果观察组总有效率为90.0%,高于对照组72.5%;观察组治疗后心功能指标LVEF、LVEDD、LVEDSD、6min步行距离及血清相关因子TNF-α、BNP、hs-CRP检测和测试情况均优于对照组,差异具统计学意义(P <0.05)。结论针对临床收治的冠心病心力衰竭患者,在美托洛尔给药基础上,取银杏叶片联用,可提高治疗效果,改善心功能及血清炎性因子水平,为获取理想预后提供了强有力的保障。
Objective To investigate the effect and prognosis of Ginkgo biloba leaves on the basis of metoprolol administration in patients with coronary heart disease and heart failure.Methods 80 patients with coronary heart disease and heart failure in our hospital from March 2017 to March 2018 were selected as the study subjects.They were randomly divided into two groups.The control group(n=40)was treated with metoprolol alone.The observation group(n=40)was treated with Ginkgo biloba leaves on the basis of metoprolol administration.The total effective rate,cardiac function and serum factor levels were compared between the two groups.Results The total effective rate was 90.0%in the observation group,which was higher than 72.5%in the control group.After treatment,the heart function indexes such as LVEF,LVEDD,LVEDSD,6-minute walking distance and serum related factors such as TNF-a,BNP and hs-CRP in the observation group were better than those in the control group,and the difference was statistically significant(P<0.05).Conclusion Ginkgo biloba leaves combined with metoprolol can improve the therapeutic effect,cardiac function and serum inflammatory factors in patients with coronary heart disease and heart failure,and provide a strong guarantee for the ideal prognosis.
作者
石家冲
SHI Jiachong(Department of Cardiology,Qianjiang Central Hospital,Qianjiang Hubei 433100,China)
出处
《中国继续医学教育》
2019年第11期161-163,共3页
China Continuing Medical Education
关键词
冠心病心力衰竭
美托洛尔
银杏叶片
心功能
炎症因子
预后
coronary heart disease
metoprolol
ginkgo leaf
heart function
inflammatory factor
prognosis
