摘要
目的探讨睾丸及睾丸旁横纹肌肉瘤的诊治方式及进展。方法回顾性分析2012年至2018年我院收治的7例睾丸及睾丸旁横纹肌肉瘤患者的临床资料。患者平均年龄(18.50±5.06)岁,肿瘤位于右侧4例、左侧3例。术前7例均行彩超、CT及MRI检查,提示睾丸肿瘤。7例均行睾丸根治性切除术,其中4例行腹腔镜下腹膜后淋巴结清扫术。术后6例行化疗,1例拒绝化疗出院。结果 7例睾丸切除手术均顺利。病理诊断6例为睾丸及睾丸旁胚胎性横纹肌肉瘤,1例为胚胎性伴局部多形性横纹肌肉瘤。4例腹腔镜淋巴结清扫手术顺利,术后无明显并发症。6例化疗患者中仅1例因化疗不良反应严重而终止。7例中6例患者接受电话随访,其中3例无瘤生存,2例仍在化疗,1例Ⅳ期患者2年后因肺部、腹膜后、椎体及纵膈多发转移而死亡;1例患者拒绝化疗后失访。结论睾丸及睾丸旁横纹肌肉瘤呈高度恶性,易复发及转移,应综合治疗,睾丸根治性切除术及腹腔镜下腹膜后淋巴结清扫术联合辅助性化疗效果良好。
Objective To explore diagnosis and treatment of testicular and paratesticular rhabdomyosarcoma. MethodsThe clinical data of 7 cases with testicular and paratesticular rhabdomyosarcoma were retrospectively analyzed. Their mean age was (18.50±5.06) years old. The tumor was found on the right side in four cases while the left side in three cases. The diagnosis of testicular tumor was set up by B-ultrasound, CT and MRI. All patients underwent testicular radical resection, including 4 cases who underwent laparoscopy retroperitoneal lymph node dissection. Chemotherapy was administered in 6 cases, but 1 case refused and discharged from hospital. ResultsSeven cases of testicular surgery were completed successfully. Pathological examination revealed embryonal rhabdomyosarcoma in 6 cases, embryonal and local pleomorphism in 1 case. Four cases of laparoscopy lymph node dissections were completed successfully without surgical complications. Chemotherapy was administered successfully in 5 patients;due to serious side effects, 1 case terminated. During a follow-up by telephone till now, 3 patients survived, 2 cases still received chemotherapy, 1 case died of recurrent disease, 1 case lost to follow-up. ConclusionsTesticular and paratesticular rhabdomyosarcoma is highly malignant with a frequent tendency of recurrence and metastasis. Orchiectomy and laparoscopy retroperitoneal lymph node dissection should be performed in patients, and it is effective in combination with adjuvant chemotherapy.
作者
郭培超
孟庆军
高宇奎
崔林刚
魏寅生
田雨冬
苏杨
连朋超
于海舟
GUO Peichao;MENG Qingjun;GAO Yukui;CUI Lingang;WEI Yinsheng;TIAN Yudong;SU Yang;LIAN Pengchao;YU Haizhou(Department of Urology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China)
出处
《现代泌尿生殖肿瘤杂志》
2019年第1期43-46,共4页
Journal of Contemporary Urologic and Reproductive Oncology
关键词
睾丸
横纹肌肉瘤
诊断
治疗
Testis
Rhabdomyosarcoma
Diagnosis
Treatment
作者简介
通信作者:孟庆军,E-mail:mengqj11@163.com.
