摘要
目的分析2017~2018年冬季流感在西北地区的流行特征,为流感防控提供依据。方法对2017年11月1日至2018年2月15日因流感样症状在西安交通大学第一附属医院门诊和急诊就诊患者基本资料及实验室检查结果进行分析。结果甲型流感高峰为2017年第52周至2018年第3周,乙型流感高峰为2018年第3周至第5周。学龄前儿童临床流感病例人数最多,共1051例(42.00%);其次为青壮年492例(22.16%);老年最少仅85例(6.94%)。各年龄组流感病毒抗原检测差异均有统计学意义(P﹤0.01)。临床流感病例中无性别差异。与乙型流感相比,甲型流感患者白细胞数目较高(7.07±0.09)×10^9/L比(5.97±0.17)×10^9/L,中性粒细胞百分比较高(59.83±0.05)%比(52.2±0.29)%,超敏C反应蛋白较高(6.15±0.11)mg/L比(5.04±0.26)mg/L,淋巴细胞百分比更低(20.0±0.02)%比(24.32±0.04)%(P值均﹤0.01)。结论2017~2018冬季流感在西北地区的流行特征为甲型、乙型流感高峰部分重叠、交错出现;学龄前儿童和青壮年为主要患病人群;感染者常伴有全身炎症指标的升高。在疫情流行时,应积极采取综合性防控措施。
Objective To analyze the characteristics of influenza(Flu)in northwest region from November 2017 to February 2018 for providing a scientific baksis for influenza prevention and control.Methods Influenza-like illness outpatients in the First Affiliated Hospital of Xi’an Jiaotong University from 1st November 2017 to 15th February 2018 were enrolled.Then to get the epidemic trend,age distribution and characteristics of laboratory examinations,patients with influenza screening test positive were analyzed.Results The peak of the number of outpatients diagnosed with A influenza was from the fifty-second week of 2017 to the third week of 2018.For B influenza,the peak was from the third week to the fifth week of 2018.0~6 years old group was the main population of Flu,1 051(positive rate was 42.00%),followed by adults,494(positive rate was 22.16%).The old were the least,85(positive rate was 6.94%).There showed significant differences in influenza virus antigen detection among all age groups(P﹤0.01).There showed no gender difference in clinical influenza cases.Compared with B influenza,the patients diagnosed with A influenza had higher leucocyte counts(7.07±0.09)×10^9/L vs(5.97±0.1 7)×10^9/L,higher neutrophilic granulocyte percentage(5 9.83%±5.00)%vs(52.2%±29.0)%and sensitivity C reactive protein(6.15±0.11)mg/L vs(5.04+0.26)mg/L,w ith less percentage of lymphocytes(20.00±2.00)%vs(24.32±4.00)%(P﹤0.01).Conclusions The epidemic types of influenza virus in northwest region performes in a rule of alternative spreading.Adults and preschoolers are the susceptible population.And the patients are often accompanied with an increasement in systemic inflammatory markers.It is necessary to take effective measures to prevent and control human infection with the influenza virus.
作者
孙皎琳
刘韩韩
张琳
霍凯凯
张文娜
王亚文
石志红
Sun Jiaolin;Liu Hatihan;Zhang Lin;Huo Kaikai;Zhang Wenna;Wang Yawen;Shi Zhihong(Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 215000,China;Departmen of Medicine,Affiliated Hospital of Xi'an Jiaotong University,Xi'an 215000,China)
出处
《国际呼吸杂志》
2019年第1期41-45,共5页
International Journal of Respiration
关键词
流感
人
流行病学因素
实验室检查
Influenza,human
Epidemiological factors
Laboratory examination
作者简介
通信作者:石志红,Email:docszh@163.com
