摘要
利用蒙脱土(MMT)分别吸附3种阳离子光敏剂(meso-四(1-甲基吡啶嗡-4-基)卟吩对甲苯磺酸盐(TMPyP)、meso-四(N-甲基-4-吡啶)卟吩四氯化锌(Zn-TMPyP)、亚甲基蓝(MB)),然后均匀分散在聚乙烯醇-苯乙烯基吡啶盐缩合物(PVA-SbQ)的水溶液中,通过紫外光交联法制备出相应的光敏MMT/PS水凝胶。借助透射电子显微镜(TEM)对MMT和MMT/PS形貌结构进行分析,利用扫描电子显微镜(SEM)、热重分析仪(TGA)对3种光敏水凝胶的内部形貌、热学性能进行分析,研究其溶胀性能及对金黄色葡萄球菌的抗菌效果。结果表明:3种光敏MMT/PS水凝胶均具有良好的溶胀性能。抗菌结果显示,三者对金黄色葡萄球菌均具有一定的杀灭效果,其中负载Zn-TMPyP的水凝胶在光照条件下对金黄色葡萄球菌的杀菌率达到98.49%。
Montmorillonite(MMT)was utilized to absorb three types of cationic photosensitizers,namely,meso-tetra(4-N-methylpyridyl)porphyrine tetratosylate(TMPyP),Zn(H)meso-tetra(N-methyl-4-pyridyl)porphine tetrachloride(Zn-TMPyP)and methylene blue(MB),the as-obtained mixtures were then evenly dispersed in aqueous polyvinyl alcohol-styrylpyridine salt condensate(PVA-SbQ)solution,corresponding photoactive MMT/PS hydrogels were prepared by the assay of UV cross-linking eventually.Transmission electron microscopy(TEM)was employed to analyse morphology of MMT and one as-prepared MMT/PS hydrogel.Scanning electron microscopy(SEM)and thermogravimetric analysis(TGA)were applied to analyse the internal morphology and thermal properties of the as-prepared hydrogels.Finally,swelling properties and antibacterial effect against staphylococcus aureus(S.aureus)were investigated.The results show that three photoactive MMT/PS hydrogels are successfully prepared with good swelling properties.The as-prepared hydrogels exhibtt inactivation against S.aureus to some extent,furthermore,the hydrogel which immobilizes Zn-TMPyP reveals best inactivation efficacy,with a sterilization rate of 98.49%.
作者
董建成
葛孝栋
王清清
魏取福
DONG Jian-cheng;GE Xiao-dong;WANG Qing-qing;WEI Qu-fu(Key Laboratory of Eco-textile(Ministry of Education),Jiangnan University,Wuxi 214122,Jiangsu,China)
出处
《材料工程》
EI
CAS
CSCD
北大核心
2019年第2期56-61,共6页
Journal of Materials Engineering
基金
2018年江苏省研究生科研创新计划项目(KYCX18_1835)
国家青年自然科学基金项目(51603090)
中央高校基本科研业务费专项资金(JUSRP51621A)
关键词
蒙脱土
水凝胶
光敏抗菌
金黄色葡萄球菌
montmorillonite
hydrogel
photodynamic antibacterial inactivation
staphylococcus aureus
作者简介
通讯作者:魏取福(1964—),男,教授,博士,从事功能纺织材料方面的研究工作,联系地址:江苏省无锡市江南大学生态纺织教育部重点实验室(214122),E-mail:qfwei@jiangnan.edu.cn
