摘要
目的探讨奥曲肽联合艾司奥美拉唑治疗急性非静脉曲张性上消化道出血的效果。方法将80例急性非静脉曲张性上消化道出血患者随机分为两组,各40例。两组患者均接受消化内科常规治疗。对照组给予艾司奥美拉唑治疗,观察组给予奥曲肽联合艾司奥美拉唑治疗。比较两组患者治疗后胃内pH值、输血量、止血时间和治疗效果。结果治疗后,观察组患者止血时间明显短于对照组(P<0.05),输血量明显少于对照组(P<0.01),胃内pH值明显高于对照组(P<0.01);观察组患者治疗效果优于对照组(P<0.05)。结论奥曲肽联合艾司奥美拉唑可升高急性非静脉曲张性上消化道出血患者胃内的pH值,止血快,疗效好。
Objective To evaluate the clinical effects of octreotide plus esomeprazole in treatment of acute,nonvariceal upper gastrointestinal bleeding(UGIB).Methods Eighty cases of acute non variceal upper gastrointestinal bleeding were randomly divided into control group and observation group,with 40 cases in each group.The control group were treated with esomeprazole,and the observation group were done with octreotide besides esomeprazole.Relevant data,including main outcomes of gastric fluid volume and gastric pH,amount of blood transfusion and hemostasis time,were extracted after treatment.Results After treatment,both of the hemostasis time and amount of blood transfusion in the observation group reduced statistically compared with the control group(P<0.05 or P<0.01),and the gastric pH and total effective rate of the observation group were higher than the control group(P<0.05 or P<0.01).Conclusion Octreotide combined with esomeprazole raised gastric pH,shorten hemostasis time and achieved an ideal efficacy in treating acute UGIB.
作者
麦绮彬
宋慧东
温凌
MAI Qibin;SONG Huidong;WEN Ling(Department of Gastroenterology,the 12th Hospital in Guangzhou,Guangdong 510620,China)
出处
《白求恩医学杂志》
2018年第5期453-454,共2页
Journal of Bethune Medical Science
