摘要
目的分析支气管哮喘接受孟鲁司特钠片联合布地奈德福莫特罗粉吸入剂治疗的临床效果。方法选择2016年7月—2018年6月中的120例支气管哮喘患者,其中接受孟鲁司特钠片联合布地奈德福莫特罗粉吸入剂治疗的患者有60例,接受孟鲁司特钠片治疗的有60例,相应视作观察组、对照组,比较治疗效果。结果观察组治疗后总有效率为91.67%,明显高于对照组总有效率70.00%,差异有统计学意义(χ2=9.090 1,P=0.002 6);观察组治疗后日间咳嗽以及夜间咳嗽评分均明显低于对照组,观察组治疗后FEF25%、FEF50%、FEF75%结果均明显高于对照组,差异有统计学意义(P<0.05);观察组用药后不良反应发生率为8.33%,与对照组不良反应发生率6.67%差异无统计学意义(χ2=0.120 1,P=0.728 9)。结论孟鲁司特钠片联合布地奈德福莫特罗粉吸入剂治疗支气管哮喘的效果要明显优于孟鲁司特钠片单一用药,且不会影响治疗安全性,可推广。
Objective To analyze the clinical effect of bronchial asthma in the treatment of montelukast sodium tablets combined with budesonide momotrol powder inhalation. Methods A total of 120 patients with bronchial asthma were enrolled between July 2016 and June 2018. Of these, 60 patients were treated with montelukast sodium tablets combined with budesonide formoterol powder inhalation, 60 cases were treated with special sodium tablets, which were regarded as observation group and control group, and the therapeutic effects were compared. Results The total effective rate of the observation group was 91.67%, which was significantly higher than the total effective rate of the control group by 70.00%, the different was statistically significant(χ2=9.0901, P=0.0026). The daytime cough and nighttime cough scores in the observation group were significantly lower than those in the control group. The results of FEF25%, FEF50% and FEF75% in the observation group were significantly higher than those in the control group, the different was statistically significant(P<0.05). The incidence of adverse reactions in the observation group was 8.33%, which was not significantly different from the incidence of adverse reactions in the control group (6.67%), without significant difference,(χ2=0.1201, P=0.7289). Conclusion The efficacy of montelukast sodium tablets combined with budesonide fumotrol powder inhalation in the treatment of bronchial asthma is significantly better than that of montelukast sodium tablets, and it will not affect the safety of treatment.
作者
贾贵敏
JIA Gui-min(Department of Pharmacy,Qixia District Hospital,Nanjing,Jiangsu Province,210046 China)
出处
《世界复合医学》
2018年第6期42-44,共3页
World Journal of Complex Medicine
作者简介
贾贵敏(1978-),女,江苏南京人,专科,主管药师,研究方向:西药学。
