摘要
目的试论临床对高血压患者应用替米沙坦治疗期间不同给药时间对治疗效果的影响。方法随机抽选于2017年7月—2018年7月我院收治的96例高血压患者,均接受替米沙坦治疗,并依照不同给药时间分为两组。对照组(n=48)为晨间给药,观察组(n=48)为晚间给药。将2组在治疗前后的血压参数变化情况、杓型高血压发生情况进行对比评价。结果治疗前,2组的各项血压参数对比差异无统计学意义(P> 0.05);治疗后,观察组的血压低于对照组(P <0.05);相比于对照组,观察组的后杓型高血压发生率较高(P<0.05)。结论高血压患者应用替米沙坦治疗期间,晚间给药可最大化实现降压效果,血压控制良好,可有效避免发生非杓型高血压,医学价值高。
Objective To discuss the influence of different administration time during telmisartan treatment period in patients with hypertension.Methods 96 cases of patients with hypertension and who treated in our hospital from July 2017 to July 2018 were randomly selected,and all patients were received telmisartan treatment.And,they were divided into two groups according to different dosing time.The control group(n=48)was given morning administration,and observation group(n=48)were given evening administration.Then,the changes of blood pressure parameters and the occurrence of dipper type hypertension before and after treatment of two groups were compared and evaluated.Results Before treatment,there was no significant difference in blood pressure parameters between the two groups(P>0.05).After treatment,the blood pressure in the observation group was lower than that in the control group(P<0.05).Compared with the control group,the incidence of dipper hypertension in the observation group was higher(P<0.05).Conclusion During telmisartan treatment in patients with hypertension,which the evening administration can maximize the effect of lowering blood pressure,the blood pressure control are good,and can effectively avoid non dipper hypertension.
作者
余国栋
YU Guodong(Department of Emergency,the Fourth People's Hospital of Huangshi City,Huangshi Hubei 435006,China)
出处
《中国继续医学教育》
2019年第2期127-129,共3页
China Continuing Medical Education
关键词
高血压
替米沙坦
杓型高血压
血压参数
晨间给药
晚间给药
hypertension
telmisartan
dipper hypertension
blood pressure parameters
morning administration
evening administration
