摘要
目的研究辛伐他汀与美托洛尔联合治疗心律失常的临床效果。方法选取2016年1月至2018年6月入院治疗的234例心律失常患者为研究对象,按照随机数字表法将其分为A、B、C组,每组78例。A、B、C组分别采用辛伐他汀、美托洛尔、辛伐他汀联合美托洛尔进行治疗。比较三组的治疗效果。结果 C组治疗总有效率明显高于A、B组(P<0.05)。三组各不良反应发生率无显著差异(P>0.05)。治疗后,三组房性收缩、室性收缩次数均减少,且C组均明显少于A、B组(P<0.05)。结论美托洛尔与辛伐他汀联合治疗心律失常的效果显著,可明显减少患者的房性收缩、室性收缩次数,且不会增加不良反应。
Objective To study the clinical effect of simvastatin combined with metoprolol in the treatment of arrhythmia.Methods A total of 234 patients with arrhythmia admitted in the hospital from January 2016 to June 2018 were selected as the study objects.They were divided into group A,B and C according to the random number table method,with 78 cases in each group.The group A,B and C were treated with simvastatin,metoprolol,simvastatin combined with metoprolol respectively.The therapeutic effects of the three groups were compared.Results The total effective rate of treatment in the group C was significantly higher than that in the group A and B(P<0.05).There were no significant differences in the incidences of adverse reactions among the three groups(P>0.05).After treatment,the numbers of atrial and ventricular contractions in the three groups decreased,and those in the group C were significantly less than the group A and B(P<0.05).Conclusion The combined treatment of metoprolol and simvastatin has a significant effect on arrhythmia.It can significantly reduce the numbers of atrial and ventricular contractions,and does not increase the incidence of adverse reactions.
作者
马宝情
李莉
MABao-qing;LI Li(Internal Medicine-Cardiovascular Department,the Hospital of Shenmu City,Yulin 719300;Pharmacy Department,Traditional Chinese Medicine Hospital of Yulin,Yulin 719000,China)
出处
《临床医学研究与实践》
2018年第35期25-26,共2页
Clinical Research and Practice
作者简介
马宝情(1977-),男,汉族,陕西榆林人,主治医师,学士。研究方向:冠心病的介入,心律失常,心力衰竭,高血压;通讯作者:李莉,E-mail:3472064153@qq.com.
