摘要
目的分析35例术前诊断阴性的胃癌腹膜转移患者的临床特征,以进一步提高胃癌腹膜转移的早期诊断水平。方法选取术前诊断阴性的胃癌腹膜转移患者35例设为腹膜转移组,另选术前及术后均诊断为腹膜转移阴性的患者35例设为未转移组。比较两组患者的临床特征。结果腹膜转移组的CA-125阳性率、腹水发生率均高于未转移组(P<0.05);腹膜转移组的肿瘤侵及浆膜及以外率、淋巴结转移率、呈低分化率均高于未转移组(P<0.05)。结论 CA-125升高、腹水发生、肿瘤侵及浆膜以及多个淋巴结转移都是临床胃癌腹膜转移的高危因素,必要时应进行影像重建分析或腹腔镜探查,以明确诊断。
Objective To analyze the clinical characteristics of35patients with gastric cancer peritoneal metastasis with negative preoperative diagnosis to further improve the level of early diagnosis of gastric cancer peritoneal metastasis.Methods Thirty-five peritoneal metastasis patients with negative preoperative diagnosis were selected as peritoneal metastasis group,35patients with negative peritoneal metastasis before and after surgery were selected as non-metastasis group.The clinical characteristics of patients in the two groups were compared.Results The positive rate of CA-125and the incidence of ascites in the peritoneal metastasis group were higher than those in the non-metastasis group(P<0.05).The rates of invasion of serosa and its beyond,lymph node metastasis and low differentiation in the peritoneal metastasis group were higher than those in the non-metastasis group(P<0.05).Conclusion The elevation of CA-125,ascites,invasion of serosa and its beyond and multiple lymph node metastasis are risk factors for gastric cancer peritoneal metastasis.If necessary,image reconstruction analysis or laparoscopic exploration should be performed to confirm diagnosis.
作者
郭利锋
吴凯
马龙安
王云梅
陈旭
韩琴芳
GUO Li-feng;WU Kai;MA Long-an;WANG Yun-mei;CHEN Xu;HAN Qin-fang(General Surgery Department,Shaanxi Provincial Cancer Hospital,Xi'an 710065,China)
出处
《临床医学研究与实践》
2018年第35期1-2,11,共3页
Clinical Research and Practice
基金
陕西省自然科学基础研究计划(No.2017JM8155)
关键词
胃癌
腹膜转移
腹水
淋巴结转移
gastric cancer
peritoneal metastasis
ascites
lymph node metastasis
作者简介
郭利锋(1978-),男,汉族,陕西西安人,主治医师,学士。研究方向:腹部肿瘤外科相关疾病;通讯作者:韩琴芳,E-mail:121010465@qq.com.
