摘要
目的:探讨甲状腺激素、白介素-6(IL-6)水平在新生儿呼吸窘迫综合征(NRDS)患儿中的表达及意义。方法:检测146例NRDS患儿(NRDS组)和100例健康新生儿(对照组)的血清三碘甲腺原氨酸(T3)、游离三碘甲腺原氨酸(FT3)、四碘甲腺原氨酸(T4)、游离四碘甲腺原氨酸(FT4)、促甲状腺激素(TSH)及IL-6。结果:NRDS组T3、FT3、T4、FT4水平低于对照组(P <0. 05),TSH、L-6水平高于对照组(P <0. 05);不同分级NRDS患儿T3、FT3、T4、FT4、TSH、IL-6水平比较差异有统计学意义(P <0. 05)。结论:检测甲状腺激素与IL-6对NRDS的诊断及病情预测有一定的意义。
Objective:To investigate the clinical expression of thyroid hormone and interleukin-6(IL-6)levels in neonatal respiratory distress syndrome(NRDS)and its significance.Methods:Serum triiodothyronine(T3),free triiodothyronine(FT3),tetraiodothyronine(T4),free tetraiodothyronine(FT4),thyroid stimulating hormone(TSH)and interleukin-6(IL-6)were detected in 146 children with NRDS(NRDS group)and 100 healthy newborns(control group).Results:The levels of T3,FT3,T4 and FT4 in NRDS group were significantly lower than those in control group(P<0.05),and the levels of TSH and L-6 were significantly higher than those in control group(P<0.05).The levels of T3,FT3,T4,FT4,TSH and IL-6 in children with different grades of NRDS were statistically significant(P<0.05).Conclusion:Detection of thyroid hormone and IL-6 has certain significance in the diagnosis and prediction of NRDS.
作者
张娜
张涛
ZHANG Na;ZHANG Tao(Anyang Sixth People's Hospital,Anyang 455000,China;Anyang Tumor Hospital)
出处
《包头医学院学报》
CAS
2018年第11期57-58,共2页
Journal of Baotou Medical College
关键词
新生儿呼吸窘迫综合征
甲状腺激素
白介素-6
Neonatal respiratory distress syndrome(NRDS)
Thyroid hormone
Interleukin-6(IL-6)
