摘要
骨折常常需要内固定物的辅助以促进愈合。传统的不可降解内固定物由于组织反应、应力遮挡等常需要二次手术取出。目前,可降解内固定物是生物材料研究领域的热点。聚乳酸作为一种较为成熟的可降解内固定物,已实际投入临床使用,由于其机械性能较差,多应用于颌骨的非承重部位。镁合金是现在可降解内固定物的研究热点,但是其降解速率过快,降解产生氢气是其主要缺点。有关锌合金内固定物的研究较少,其十分具有发展潜力,很可能成为新一代可降解内固定系统。本文将对聚乳酸、镁合金、锌合金作为内固定系统进行综述。
Internal fixation is often applied to promote fracture healing.Traditional non-degradable internal fixations often require secondary surgical removal because of tissue reaction and stress shielding effect.At present,the degradable internal fixation is a hot topic in the field of biological material research.Polylactic acid,as a more mature degradable internal fixation material,has been clinically applied.Because of its poor mechanical properties,it is widely used in non-load bearing parts of the cranio-facial region.Magnesium alloy is a research hotspot in the field of biodegradable internal fixation.Its main disadvantage is its fast degradation rate and hydrogen release.There are few studies on zinc alloy internal fixations,which have great development potential and are very likely to become a novel degradable internal fixation system.This article will review polylactic acid,magnesium alloys,and zinc alloys as internal fixation systems.
作者
邵小夕
王祥
许方方
戴太强
刘斌
刘彦普
Shao Xiaoxi;Wang Xiang;Xu Fangfang;Dai Taiqiang;Liu Bin;Liu Yanpu(State Key Laboratory of Military Stomatology,National Clinical Research Center for Oral Diseases,Shaanxi Key Laboratory of Oral Diseases,Department of Cranio.Facial Trauma and Orthognathic Surgery,School of Stomatology,The Fourth Military Medical University,Xi′an 710032,China;State Key Laboratory of Military Stomatology,Laboratory Animal Center,School of Stomatology,The Fourth Military Medical University,Xi′an 710032,China)
出处
《中华口腔医学研究杂志（电子版）》
CAS
2018年第5期317-321,共5页
Chinese Journal of Stomatological Research(Electronic Edition)
基金
军事口腔医学国家重点实验室自主研究课题(2017ZA02)
关键词
生物可降解材料
内固定器
聚乳酸
镁合金
锌合金
Biodegradable materials
Internal fixators
Polylactic acid
Magnesium alloys
Zinc alloys
作者简介
通信作者:刘彦普,电子邮箱:liuyanpu@fmmu.edu.cn。
