摘要
目的观察依托咪酯对普外科手术患者血浆皮质醇及术后认知功能水平分析的影响。方法选取自2016年1月至2017年1月于我院手术室接受全身麻醉的普外科手术患者60例,试验组与对照组均应用信封法随机分组,对照组30例,应用瑞芬太尼联合丙泊酚麻醉,试验组30例,应用依托咪酯及瑞芬太尼麻醉,观察两组患者手术前后血浆皮质醇水平及认知功能MMSE评估情况。结果试验组患者麻醉后血浆皮质醇水平明显低于对照组,术后认知能力损害小于对照组,有统计学差异(P<0.05)。结论依托咪酯应用于普外科手术静脉麻醉,安全有效,值得推广应用。
Objective To observe the effect of etomidate on plasma cortisol and postoperative cognitive function in patients undergoing Department of general surgery surgery.Methods From January 2016 to January 2017 in our hospital operation room department of general surgery surgery received 60 patients with general anesthesia of the patients,the experimental group and the control group were applied randomly into the control group of 30 cases,the application of remifentanil combined with propofol anesthesia,30 cases of experimental group,application of etomidate and remifentanil anesthesia,two groups were observed before and after surgery in patients with plasma cortisol levels and cognitive function assessment MMSE.Results The level of serum cortisol in the experimental group was significantly lower than that in the control group,and the cognitive impairment was less than that of the control group(P<0.05).Conclusion etomidate intravenous anesthesia used in general surgery,is safe and effective,it is worthy of popularization and application.
作者
岳彬
YUE Bin(Department of Anesthesiology,Dalian Friendship Hospital,Dalian 116001,China)
出处
《中国医药指南》
2018年第23期12-13,共2页
Guide of China Medicine
关键词
依托咪酯
普外科
血浆皮质醇
认知功能
Etomidate
Department of general surgery
Plasma cortisol
Cognitive function
