摘要
从牛角瓜(Calotropis gigantea)根的乙醇粗提物中分离出9个化合物,通过质谱(MS)、核磁共振谱(NMR)等分析方法,鉴定了它们的结构.分别为洋地黄毒甙元-3-O-β-D-葡萄糖甙(1)、洋地黄毒甙元-3-O-α-L-鼠李糖甙(2)、坎诺甙元-3-O-β-D-葡萄糖甙(3)、坎诺甙元-3-O-α-L-鼠李糖甙(4)、齐墩果烷-12-烯(5)、羽扇豆醇(6)、奈皮菌素(7)、3α,11α-二羟基-20(29)-羽扇豆烷-28-酸甲酯(8)和熊果酸(9),其中,化合物1～4为强心苷类化合物,5～9为三萜或甾体类化合物,化合物1～3,5为首次从该植物中分离得到.
In this paper,nine compounds are isolated from the ethanol crude extract of the roots of Calotropis gigantean and their structures were identified by means of mass spectrometry(MS)and nuclear magnetic resonance spectrum(NMR)as:digitoxigenin-3-O-β-D-glucoside(1),digitoxigenin-3-O-α-L-rhamnoside(2),cannogenin-3-O-β-D-glucoside(3),cannogenin-3-O-α-L-rhamnoside(4),olean-12-ene(5),lupeol(6),nepeticin(7),3α,11α-dihydroxy-20(29)-lup-28-oic acid methyl ester(8)and ursolic acid(9),respectively.Among them,the compounds 1~4 are cardiac glycosides,the compounds 5~9 are triterpenes or steroids.In addition,the compounds 1~3 and 5 are isolated from the plant for the first time.
作者
杨彩霞
马成龙
郜晓玲
杨军辉
高非
YANG Cai-xia;MA Cheng-long;GAO Xiao-ling;YANG Jun-hui;GAO Fei(Key Laboratory of Polymer Materials of Gansu Province,Key Laboratory of Eco-Environment Related Polymer Materials of Ministry of Education,College of Chemistry and Chemical Engineering,Northwest Normal University, Lanzhou 730070,Gansu,China;Key Laboratory of Crop Gene Resources and Germplasm Enhancement in Southern China,Ministry of Agriculture, Tropical Crops Genetic Resources Institute,Chinese Academy of Tropical Agricultural Sciences, Danzhou 571737,Hainan,China)
出处
《西北师范大学学报（自然科学版）》
CAS
北大核心
2018年第5期78-82,共5页
Journal of Northwest Normal University(Natural Science)
基金
西北师范大学博士后科研启动基金资助项目(NWNU-179).
关键词
萝藦科
牛角瓜根
强心苷
三萜
甾体
化学成分
Asclepiadaceae
roots of Calotropis gigantea
cardiac glycosides
triterpenes
seroids
chemical constituent
作者简介
杨彩霞(1971—),女,甘肃兰州人,副教授,博士,硕士研究生导师.主要研究方向为天然产物化学.E-mail:jltycx@126.com.
