摘要
目的:比较血管成形联合置管溶栓治疗与常规血管成形术治疗下肢动脉硬化闭塞症的临床效果。方法:选择2014年1月至2015年12月我院收治的下肢动脉硬化闭塞症患者33例,18例行常规介入治疗(常规组),15例行介入联合溶栓治疗(溶栓组),观察两组患者的踝肱指数(ABI)、血管开通率、临床疗效与并发症,随访其血管通畅情况。结果:常规组的血管开通率、临床有效率均为88.89%(16/18),溶栓组分别为93.33%(14/15)、100%(15/15)。两组的术后足背动脉搏动均增强,ABI值均较术前明显升高,其中溶栓组ABI提高幅度较常规组大,组间差异有统计学意义(P<0.05)。常规组发生血栓相关并发症2例,溶栓组无相关并发症出现。常规组术后3、6、12、24个月血管通畅率分别为83.33%(15/18)、83.33%(15/18)、72.22%(13/18)及62.50%(10/16),溶栓组分别为100%(15/15)、100%(15/15)、80.00%(12/15)及71.43%(10/14)。溶栓组血管通畅率数值高于常规组。结论:经皮血管成形联合置管溶栓治疗下肢动脉硬化闭塞症的临床效果优于常规的血管成形术。
Objective:To compare the clinical effects of angioplasty combined with catheterized thrombolysis and conventional angioplasty in the treatment of lower extremity arterial occlusive disease.Methods:From January 2014 to December 2015,clinical data of 33 patients with lower extremity ASO treated by different ways were analyzed,including 18 cases with routine interventional therapy(routine group)and 15 ones with interventional and thrombolytic therapy(thrombolysis group).The clinical results in two groups were analyzed and compared.Results:Technical success rates were 88.89%in routine group and 93.33%in thrombolysis group.The clinical total effective rate in thrombolysis group was higher than that of routine group(100%vs.88.89%).The ABI values in both groups were significantly increased after operation,and the increase rate of ABI in thrombolysis group was larger than that in routine group(P<0.05).The complications about thrombosis of thrombolysis group were lower than those of routine group.After 3,6,12 and 24 months of operation,the primary patency rates were 83.33%,83.33%,72.22%and 62.50%respectively in routine group,and 100%,100%,80.00%and 71.43%respectively in thrombolysis group.The primary patency in the thrombolysis group was much better than that in the routine group.Conclusion:For patients with ASO,the value of interventional treatment combined with thrombolysis is better than that of only routine interventional option.
作者
武兴杰
黄树圭
邓军
李军
方萍
朱威
Wu Xingjie;Huang Shugui;Deng Jun;Li Jun;Fang Ping;Zhu Wei(Department of Interventional Radiology,The First Affiliated Hospital of Guangdong University of Pharmacy,Guangzhou 510080,China;Department of Interventional Radiology,The Second Affiliated Hospital of Sun Yat-sen University,Guangzhou 510100,China)
出处
《中华介入放射学电子杂志》
2018年第3期232-236,共5页
Chinese Journal of Interventional Radiology：electronic edition
关键词
动脉硬化闭塞症
介入治疗
溶栓
下肢缺血
Arteriosclerosis obliterans
Interventional therapy
Thrombolysis
Lower limb ischemia
作者简介
通讯作者:武兴杰,Email:wuxingjie3000@163.com。
