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精准医学时代胃癌诊治的现状与进展 被引量:8

Current Status and Progress of Diagnosis and Treatment for Gastric Cancer in the Era of Precision Medicine
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摘要 精准医学作为一种全新的医学概念和医疗模式,已日益在疾病的临床诊治中体现其价值。随着基因组学、影像学诊断和外科技术的发展,恶性肿瘤的诊疗也开始逐步迈向精准医学时代。胃癌的精准外科治疗是在利用现代分子诊断技术和影像学实施精准分子分型和分期的基础上,制订精准化和个体化的外科手术方案,并将微创化和功能保留的理念贯彻其中。对于晚期胃癌应采用包括传统放化疗以及分子靶向治疗、免疫治疗在内的综合治疗手段,以进一步改善患者的预后。 As a new medical concept and medical model,precision medicine has been increasingly showing its benefits in the clinical diagnosis and treatment.With the development and progress of cancer genomics,imaging diagnosis and surgical techniques,the diagnosis and treatment of malignant tumors is gradually moving towards the era of precision medicine.The precision surgical treatment for gastric cancer is the use of modern molecular and imaging diagnostic technologies,on the basis of molecular classification and clinical staging,to develop accurate and individualized surgical plan with the concept of minimally invasive surgery and functional preservation.For the advanced gastric cancer,comprehensive treatments including chemoradiotherapy,molecular targeted therapy and immunotherapy are used to further improve the prognosis of patients.
作者 赵恩昊 赵刚 曹晖 ZHAO Enha;ZHAO Gang;CAO Hui(DepartmentofGastrointestinalSurgery,RenjiHospital,SchoolofMedicine,ShanghaiJiaoTongUniversity,Shanghai(200127))
出处 《胃肠病学》 2018年第6期321-326,共6页 Chinese Journal of Gastroenterology
关键词 精准医学 胃肿瘤 外科手术 分子靶向治疗 免疫疗法 Precision Medicine Stomach Neoplasms Surgical Procedures,Operative Molecular Targeted Therapy Immunotherapy
作者简介 赵恩昊,Email:microzhaoenhao@hotmail.com;通信作者,曹晖,Email:caohuishcn@hotmail.com
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