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借用网络数据库分析葛根化学成分及其与现代疾病的关系 被引量:3

Analysis the relationship between chemical composition of Pueraria lobata with modern disease by the network database
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摘要 葛根始载于中国最早的中药学著作《神农本草经》中,随着科技的发展和临床经验的不断积累,葛根的应用不断得到深入。本文借助TCMSP数据库、台湾中医药资料库、Batman TCM数据库对葛根成分及治疗的相关疾病进行了汇总和分析,发现不同数据库得到的结果不尽相同,其中葛根化学成分分析结果中,大豆苷、葛根素、滨蒿内酯、尿囊素为3个数据库所共有,且葛根主用于心绞痛、高血压、心力衰竭等心血管疾病的治疗。大数据时代的来临为中药的整合和深入研究带来了新的发展契机,在借助大数据便利的同时,也应重视其结果在基础实验中的验证。 Pueraria Lobata was first recorded in the book of“Shen Nong’s Materia Medica”.With the development of science and technology and the continuous accumulation of clinical experience,the application of Pueraria lobata has been deepened.Based on TCMSP database,Taiwan Chinese medicine database and Batman TCM database,this article summarized and analyzed the components and related diseases of Pueraria lobata,and found that the results obtained from different databases were different.In the chemical composition analysis of Pueraria lobata,there were 3 databases of daidzein,Gegensu,artemisinin,allantoin,and pueraria lobata was mainly used for the treatment of cardiovascular disease such as angina pectoris,hypertension and heart failure.The coming of the era of big data had brought new opportunities for the integration and further research of Chinese medicine.With the help of big data,the verification of its results in basic experiments should be attached.
作者 施伟丽 信琪琪 袁蓉 丛伟红 陈可冀 SHI Weili;XIN Qiqi;YUAN Rong(Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China)
出处 《环球中医药》 CAS 2018年第4期610-615,共6页 Global Traditional Chinese Medicine
基金 北京市"十病十药"研发专项(Z141100002214011) 北京市自然科学基金(7152125)
关键词 葛根 TCMSP数据库 台湾中医药资料库 Batman TCM数据库 Pueraria Lobata TCMSP database Taiwan TCM database Batman TCM database
作者简介 施伟丽(1987-),女,博士,在站博士后。研究方向:中药心血管病药理研究。E-mail:shiweilidoctor@163.com;袁蓉(博士研究生);通信作者:丛伟红(1972-),女,博士,研究员。研究方向:中药药理。E-mail:congcao@188.com
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