摘要
目的研究中老年男性动脉弹性与血清尿酸及血脂水平的相关性。方法选取男性体检者279例,进行体格、生化及动脉弹性检查,根据脉搏波传导速度(PWV)测定分为动脉硬化组138例,非动脉硬化组141例,分析动脉弹性与血清尿酸、血脂水平之间的相关性。结果与非动脉硬化对照组比较,动脉硬化组血清尿酸[(409.38±92.78)mmol/L比(433.84±93.43)mmol/L]、三酰甘油(TG)[(1.64±0.83)mmol/L比(2.26±1.37)mmol/L]水平显著升高(P<0.05或P<0.01),而低密度脂蛋白(LDL)、高密度脂蛋白(HDL)及总胆固醇(TCH)水平差异无统计学意义。Pearson相关性分析显示,年龄、腰围、TG与肱-踝脉搏波传导速度存在明显的正相关(r=0.169~0.439,P<0.05或P<0.01)。结论 TG水平与动脉硬化密切相关,同时高尿酸血症、肥胖、高血压及血糖异常是中老年男性动脉硬化的危险因素。
Objective To study the correlation of arterial elasticity with the levels of serum uric acid and blood lipid in middle and elderly male population.Methods A total of 279 male were enrolledand physical,biochemical and arterial elasticity tests were performed.Based on the pulse wave velocity(PWV),these were divided into two groups including non-arteriosclerosis group of 138 cases and arteriosclerosis group of 141 cases.Then we analyzed the correlation of arterial elasticity with serum uric acid and blood lipid levels.Results Compared with the non-arteriosclerosis control group,the serum levels of UA[(409.38±92.78)mmol/L VS.(433.84±93.43)mmol/L]and TG[(1.64±0.83)mmol/L VS.(2.26±1.37)mmol/L]were significantly elevated in arteriosclerosis group(P<0.05 or P<0.01),while there was no significant difference on the levels of LDL,HDL and TCh between the two groups.Pearson correlation analysis showed that there was a positive correlation of PWV with age,waist circumference and TG(r=0.169-0.439,P<0.05 or P<0.01).Conclusion TG,hyperuricemia,obesity,hypertension and abnormal blood glucose are risk factors for atherosclerosis in middle-aged and elderly men.
作者
史晓雪
唐世琪
徐丽娟
刘静
王瑾
刘化云
Shi Xiaoxue;Tang Shiqi;Xu Lijuan;Liu Jing;Wang Jin;Liu Huayun(Department of Geriatrics,Renmin Hospital of Wuhan University,Wuhan 430060,China)
出处
《中国临床保健杂志》
CAS
2018年第2期164-167,共4页
Chinese Journal of Clinical Healthcare
基金
湖北省攻关计划项目(2015BKA335)
关键词
动脉硬化
尿酸
血脂
危险因素
arteriosclerosis
uric acid
lipids
risk factors
作者简介
史晓雪,硕士在读,Email:1285621857@qq.com;通信作者:唐世琪,主任医师,硕士生导师,Email:wh88063953@qq.com
