摘要
目的探讨对糖尿病合并冠心病患者行美托洛尔治疗的临床效果。方法将2016年2月—2017年2月该院收治的108例糖尿病合并冠心病患者作为研究对象,根据临床治疗过程中所使用的剂量不同分为大剂量组和小剂量组,各54例。小剂量组行小剂量美托洛尔治疗,大剂量组行大剂量美托洛尔治疗,观察并比较两组治疗效果、治疗前后空腹血糖、餐后2 h血糖以及血脂等各项指标的变化情况。结果大剂量组的治疗有效率50例(92.59%)显著高于小剂量组42例(77.78%),两组治疗前的空腹血糖、餐后2 h血糖均差异无统计学意义(P>0.05),治疗后大剂量组的空腹血糖(6.42±0.93)mmol/L以及餐后2 h血糖(9.15±1.18)mmol/L均优于小剂量组(8.98±1.31)、(12.64±1.03)mmol/L,大剂量组的TC(3.08±0.49)mmol/L、TG(1.22±0.52)mmol/L、LDL-C(2.38±0.39)mmol/L以及HDL-C(2.02±0.28)mmol/L等指标均优于小剂量组(4.82±0.95)、(2.13±0.85)、(3.11±0.63)、(0.89±0.47)mmol/L,差异有统计学意义(P<0.05)。结论对糖尿病合并冠心病患者行大剂量美托洛尔治疗,不仅能够在一定程度上提高治疗效果,同时,还能够有效控制患者的血糖、血脂水平,利于患者的病情恢复。
Objective To study the clinical effect of metoprolol in treatment of diabetes and coronary heart disease.Methods 108 cases of patients with diabetes and coronary heart disease admitted and treated in our hospital from February 2016 to February 2017 were selected and divided into two groups with 54 cases in each according to different doses,and the small-dose group were treated with small-dose metoprolol,while the large-dose group were treated with large-dose metroprolo,and the treatment effect,fasting blood glucose before and after treatment,postprandial 2h blood glucose and blood liquid were compared between the two groups.Results The treatment effective rate in the large-dose group was obviously higher than that in the small-dose group(50 cases vs 42 cases,92.59%vs 77.78%),and there were no obvious differences in the fasting blood glucose and postprandial 2h blood glucose before treatment between the two groups were not obvious(P>0.05),after treatment,the fasting blood glucose,and the postprandial 2 h blood glucose in the large-dose group were better than those in the small-dose group,[(6.42±0.93),(9.15±1.18)mmol/L vs(8.98±1.31),(12.64±1.03)mmol/L],and the TC,TG,LDL-C and HDL-C in the large-dose group were better than those in the small-dose group,[(3.08±0.49),(1.22±0.52),(2.38±0.39),(2.02±0.28)mmol/L vs(4.82±0.95),(2.13±0.85),(3.11±0.63),(0.89±0.47)mmol/L](P<0.05),and the differences were obvious.Conclusion The large-dose metoprolol in treatment of diabetes and coronary heart disease can not only improve the treatment effect to a certain degree,and it also can control the blood glucose and blood liquid levels of patients and it is conducive to the recovery of diseases.
作者
李蕾
张明德
王后丹
徐少全
蒋希石
LI Lei;ZHANG Ming-de;WANG Hou-dan;XU Shao-quan;JIANG Xi-shi(Department of Endocrinology,Liaocheng Dongchangfu People’s Hospital,Liaocheng,Shandong Province,252000 China)
出处
《系统医学》
2017年第17期43-45,共3页
Systems Medicine
关键词
美托洛尔
糖尿病
冠心病患者
血糖水平
血脂指标
Metoprolol
Diabetes
Patients with coronary heart Disease
Blood glucose level
Blood liquid index
作者简介
李蕾(1982-),女,山东聊城人,本科,主治医师,主要从事内分泌专业的工作。;[通讯作者]蒋希石(1983-),男,山东聊城人,本科,主治医师,研究方向:急诊医学,E-mail:625372538@qq.com。
