摘要
小细胞肺癌(SCLC)在肺癌中所占比例为15%~20%,其恶性程度高,在诊断时多已发生远处转移。虽然在治疗时发现其对化疗、放疗敏感性高,其长期预后差,诊断后5年生存率为5%~10%。影响SCLC临床症状、治疗效果、预后的因素有很多,本研究就人口学特征、临床分期、血清学标志物、肿瘤标志物、免疫组织标志物等对SCLC预后的影响作一综述。
Small cell lung cancer(SCLC)currently accounts for 15%to 20%in all lung cancers with a high malignant degree and it is usually diagnosed with distant metastasis.Although SCLC has a high sensitivity to chemotherapy and radiotherapy,its long-term prognosis is relatively poor and its five-year survival rate is 5%to 10%.Many factors could influence SCLC on clinical symptoms,therapeutic effects and prognosis.This paper reviewed the effects of demographic characteristic,clinical stage,serum markers,tumor markers and immunohistochemical markers on the prognosis of SCLC.
作者
夏国庆
韩一平
XIA Guo-qing;HAN Yi-ping(Department of General Practice,Changhai Hospital,Shanghai 200433,China;Department of Respiratory and Critical Care Medicine,Changhai Hospital,Shanghai 200433,China)
出处
《中国全科医学》
CAS
北大核心
2018年第11期1372-1377,共6页
Chinese General Practice
关键词
小细胞肺癌
预后
影响因素
综述
Small cell lung carcinoma
Prognosis
Influence factors
Review
作者简介
通信作者:韩一平,主任医师,教授;E-mail:yphan2006@163.com
