摘要
利用氧化还原反应制备纳米银-石墨烯复合纳米材料(Ag NPs-GN),将其修饰在玻碳电极表面制备了纳米银-石墨烯修饰玻碳电极(Ag NPs-GN/GCE)。在p H 4.78的Britton-Robinson(B-R)缓冲溶液中,用循环伏安法(CV)和方波伏安法(SWV)研究了对乙酰氨基酚在Ag NPs-GN/GCE和GN/GCE上的电化学行为。结果表明,二者对对乙酰氨基酚的氧化还原反应均有电催化作用,而且复合纳米材料Ag NPs-GN具有较单一GN更好的催化效果。用方波伏安法测得对乙酰氨基酚的还原峰电流与其浓度在1.0×10-7~5.0×10-4mol/L范围内呈线性关系,检出限(S/N=3)为3.0×10-8mol/L。建立了片剂中对乙酰氨基酚含量测定的新方法,修饰电极具有较好的重现性和稳定性。
In this work,an Ag nanoparticles-graphene composite nanomaterial(AgNPs-GN)was prepared by redox reaction.And an Ag nanoparticles-graphene modified glass carbon electrode(AgNPs-GN/GCE)was fabricated by immobilizing AgNPs-GN on the surface of the glass carbon electrode.The electrochemical behaviors of paracetamol on AgNPs-GN/GCE and GN/GCE were investigated in B-R buffer solution(pH 4.78)by cyclic voltammetry and square wave voltammetry.Both modified electrodes had electrocatalytic activity for the redox of paracetamol,and the AgNPs-GN/GCE possessed a more excellent electrocatalytic effect.Under the optimal conditions,the reduction peak current of paracetamol was proportional to its concentration in the range of 1.0×10-7-5.0×10-4 mol/L with the detection limit of 3.0×10-8 mol/L.A new method for the determination of paracetamol in tablets was established.The modified electrode showed an excellent stability and a good reproducibility.
作者
张亚
王燕
马亚军
ZHANG Ya;WANG Yan;MA Ya-jun(Department of Chemistry and Chemical Engineering,Yulin College,Yulin 719000,China)
出处
《分析测试学报》
CAS
CSCD
北大核心
2018年第3期319-323,共5页
Journal of Instrumental Analysis
基金
国家自然科学基金项目(21663033)
陕西省科技厅项目(2017JM2039)
关键词
对乙酰氨基酚
纳米AG
石墨烯
修饰电极
电催化
paracetamol
Ag nanoparticles
graphene(GN)
modified electrode
electrocatalysis
作者简介
通讯作者:张亚,博士,教授,研究方向:电分析化学,Tel:0912-3891144,E-mail:zhangya1103@126.com
