摘要
目的探讨经鼻持续气道正压通气治疗重症肺炎的临床效果。方法选取四川省凉山彝族自治州妇幼保健计划生育服务中心2015年12月—2017年8月收治的重症肺炎患儿128例,随机分为对照组和试验组,各64例。对照组患儿采用头罩吸氧或鼻导管吸氧,试验组患儿经鼻持续气道正压通气治疗。比较两组患儿治疗前后各项临床指标(心率、呼吸频率、危重症评分)改善情况、血气分析指标[血氧分压(PaO_2)、血二氧化碳分压(PaCO_2)、HCO_3^-)]改善情况及临床效果,观察患儿治疗期间不良反应发生情况。结果治疗前,两组患儿心率、呼吸频率、危重症评分及PaO_2、PaCO_2、HCO_3^-比较,差异无统计学意义(P>0.05);治疗后,试验组患儿心率、呼吸频率及危重症评分低于对照组,PaO_2、PaCO_2、HCO_3^-高于对照组(P<0.05)。试验组患儿临床疗效优于对照组(P<0.05)。两组患儿均未出现严重不良反应。结论采用经鼻持续气道正压通气治疗重症肺炎患儿的临床疗效确切,可明显改善患儿的临床症状及体征,且安全性好。
Objective To explore the clinical effect of nasal continuous positive airway pressure on severe neonatal pneumonia.Methods A total of128cases of severe pneumonia children were admitted from December2015to August2017in Maternal and Child Health Care Family Planning Service Center,which were randomly divided into control group and experimental group,64cases in each group.Control group was given oxygen absorption via hood or oxygen inhalation via nasal tube,experimental group was given nasal continuous positive airway pressure.The clinical indicators(HR,respiratory rate,critical illness scores)and blood gas analysis indexes(PaO2,PaCO2,HCO3-)before and after treatment and clinical effect were compared between the two groups,and the incidence of adverse reactions were observed.Results Before treatment,no significant differences of HR,respiratory rate,critical illness scores or PaO2,PaCO2,HCO3-was found between the two groups(P>0.05);after treatment,the experimental group of HR,respiratory rate and critical illness scores were lower than control group,PaO2,PaCO2,HCO3-were higher than control group(P<0.05).The clinical effect of experimental group was better than control group(P<0.05).No serious adverse reactions was happened.Conclusion Nasal continuous positive airway pressure has an exactly clinical effect on severe neonatal pneumonia,it can effectively improve the clinical symptoms and signs,and with good safety.
作者
罗刚群
LUO Gang-qun(Maternal and Child Health Care Family Planning Service Center,Liangshan Yi Autonomous Prefecture 615000,China)
出处
《实用心脑肺血管病杂志》
2017年第B12期39-41,共3页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
肺炎
经鼻持续气道正压通气
新生儿
效果
Pneumonia
Nasal continuous positive airway pressure
Neonate
Effect
