摘要
目的分析颈项透明层(nuchal translucency,NT)与颈后皮肤皱褶(nuchal fold,NF)在胎儿染色体异常检测中的应用价值。方法选取2015年1月至2016年12月本院经产科超声检查提示为NT和NF增厚的孕妇69例作为研究对象,所有孕妇均行介入性产前诊断,分析NT和NF对染色体异常检出率的影响。结果超声检查提示:NT增厚孕妇共35例,绒毛培养发现染色体异常8例,检出率为22.9%。超声检查提示:NF增厚孕妇共34例,羊水培养发现染色体异常4例,检出率为11.8%。结论 NT和NF增厚在染色体异常胎儿筛查中具有重要的应用价值,能够尽早发现孕早/中期的染色体异常胎儿。
Objective To analyze the value of nuchal translucency(NT)and nuchal fold(NF)in the detection of fetal chromosomal abnormalities.Method From January2015to December2016,69pregnant women who underwent obstetric ultrasonography for NT and NF in our hospital were selected as research subjects.All pregnant women underwent interventional prenatal diagnosis,the detection rates of NT and NF on chromosomal abnormalities were analyzed.Result Ultrasonography showed that there were35pregnant women with NT thickening,8cases of chromosomal abnormalities found in villus culture,the detection rate was22.9%.Ultrasonography showed that there were34pregnant women with NF thickening,4cases of chromosomal abnormalities were found in amniotic fluid culture,the detection rate was11.8%.Conclusion The thickening of NT and NF in fetal screening of chromosomal abnormalities has an important value in application.Early detection of fetal chromosomal abnormalities in early/middle gestational stages.
作者
安晓玲
郝荣
张春燕
AN Xiao-ling;HAO Rong;ZHANG Chun-yan(Department of Ultrasonography, Northwest Women's and Children's Hospital, Xi'an 710061, China)
出处
《中国医学前沿杂志（电子版）》
2017年第12期102-104,共3页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
作者简介
通讯作者:张春燕 E-mail :2548226991@qq.com
