摘要
目的探讨临床药师参与药物相互作用引起不良反应处理的药学实践。方法分析1例再生障碍性贫血儿童联合使用环孢素(Cs A)与伏立康唑引起的高血压原因及处理。结果 Cs A可能导致患儿持续性高血压,除需进行Cs A剂量调整,必要时需使用降压药物治疗,在遴选降压药物时亦应考虑其与Cs A的药物相互作用。结论临床药师可以通过分析药物相互作用,参与药物相关性不良反应处理,体现在治疗团队中的价值。
ObjectiveTo investigate the pharmacy practice of clinical pharmacists'attendance in the treatment of adverse reactions caused by drug interactions.MethodsAnalysis was conducted on the causes and treatment of hypertension in one pedinatric patient with aplastic anemia induced by combined use of cyclosporine and voriconazole.ResultsCyclosporine A could lead to prolonged hypertension.Cyclosporine A dosage should be adjusted;antihypertensive drugs should be used in necessity.When choosing antihypertensive drugs,drug interaction with cyclosporine A should be considered.ConclusionClinical pharmacists could manage adverse drug reactions by analyzing drug interactions,and offer suggestions for ADR patients.
作者
吴劲东
仇锦春
张永
WU Jindong;QIU jinchun;ZHANG Yong(Women and Children's Hospital of Sanshui Foshan,Foshan 528100,China;Children's Hospital,Nanjing Medical University,Nanjing 210000,China)
出处
《医药导报》
CAS
2017年第12期1419-1421,共3页
Herald of Medicine
基金
南京市医学科技发展专项资金资助项目(YKK14112)
江苏省药学会-百特生物药学基金科研项目(201507)
作者简介
吴劲东(1986-),男,安徽佛山人,药师,硕士,主要从事小儿用药临床药学工作。电话:0757-87800916,E-mail:184810474@qq.com。;通信作者，张永(1980-),男,江苏南京人,主管药师,硕士,主要从事小儿用药临床药学工作。电话:025-83117533,E-mail:fusematic@163.com。
