摘要
miRNA(MicroRNAs)是一类具有调节靶基因表达的18-25个短核甘酸序列组成的非编码核糖核苷酸分子。miRNA在机体的正常发育及病理过程中发挥极其重要的生物学功能。目前我国肺癌发病率日益上升,肺癌的早期诊断及治疗却面临着极大地困难。大量临床研究表明,miRNA在肺癌的筛查、诊断、治疗及预后中起着重要的应用价值。
MiRNA(MicroRNAs)is a class of small non-coding RNAs(18nt^25nt)that regulate the expression of target genes.MiRNA plays key roles in normal development and pathological processes of body.At present,lung cancer has been rapidly rising inincidence in china,but the early diagnosis and treatment of early-stage lung cancer are facing great difficulties.Many clinical studiesshowed that miRNA has important value in the screening,diagnosis treatment and prognosis of lung cancer.
作者
王晓琼
张玲玲
王江洪
孙岩
WANG Xiao-qiong;ZHANG Ling-ling;WANG Jiang-hong;SUN Yan(Medical College, Zhengzhou University of Industrial Technology, Xinzheng 451150, China)
出处
《唐山师范学院学报》
2017年第5期65-68,共4页
Journal of Tangshan Normal University
关键词
MIRNA
肺癌
筛查
诊断
治疗
预后
miRNA
lung cancer
screening
diagnosis
treatment
prognosis
作者简介
王晓琼（1988-），女，河南三门峡人，硕士，助教，研究方向为分子生物学
