摘要
目的:探讨不同降压药联合应用对老年高血压患者血压变异性的影响。方法:收治老年原发性高血压患者120例,按照随机数字法分为A、B两组,各60例。A组给予氨氯地平联合缬沙坦治疗,B组给予缬沙坦联合氢氯噻嗪治疗。结果:服药12周后24 h SBP、24 h SBPV均较治疗前明显降低(P<0.05),但A组24 h SBPV下降更为明显(P<0.05)。与治疗前相比,服药12周后24 h DBP、24 h DBPV下降的幅度更为明显(P<0.05),A组24 h DBPV的下降幅度明显低于B组(P<0.05)。结论:老年原发性高血压患者应用氨氯地平或氢氯噻嗪与缬沙坦联合治疗,可取得显著的效果。
Objective:To investigate the effect of different antihypertensive drugs combined application on blood pressurevariability in elderly hypertensive patients.Methods:120elderly patients with primary hypertension were selected.They wererandomly divided into the A group and B group with60cases in each group.The A group was treated with amlodipine combinedwith valsartan,and B group was treated with valsartan and hydrochlorothiazide.Results:After12weeks,24h SBP,24h SBPV weresignificantly lower than those before the treatment(P<0.05),but the decrease of24h SBPV in A group was more obvious(P<0.05).Compared with before the treatment,the decrease of24h DBP and24h DBPV was more obvious(P<0.05)after12weeks,and thedecrease of24h DBPV in A group was lower than that in group B(P<0.05).Conclusion:For elderly patients with primaryhypertension,amlodipine or hydrochlorothiazide combined with valsartan can achieve significant results.
作者
王萌
Wang Meng(Doudian Community Health Service Center of Fangshan District,Beijing City 102433)
出处
《中国社区医师》
2017年第27期16-17,共2页
Chinese Community Doctors
关键词
氢氯噻嗪
缬沙坦
氨氯地平
高血压
血压变异性
Hydrochlorothiazide
Stan
Amlodipine
Hypertension
Blood pressure variability
