摘要
目的:探讨磷酸奥司他韦颗粒在流感样患儿治疗中的应用效果。方法:选取我院儿科收治的90例流感样患儿,按照患儿的入院时间将其随机分为对照组和观察组各45例,对照组予以利巴韦林注射治疗,观察组患儿在对照组基础上应用磷酸奥司他韦颗粒,对比两组患者的治疗效果、临床症状缓解时间以及用药后的不良反应情况,另外比较两组患儿家长对治疗的满意率。结果:观察组与对照组的治疗有效率分别为97.8%、84.4%,观察组患儿的治疗有效率高于对照组,两组间差异明显,P<0.05;对照组与观察组的不良反应发生率分别为8.9%、11.1%,两组不良反应无显著差异,P<0.05;观察组的临床症状缓解时间短于对照组,两组间差异显著,P<0.05;观察组患儿家长对治疗的满意率95.6%高于对照组患儿家长对治疗的满意率84.4%,P<0.05。结论:在流感样病例小儿中应用磷酸奥司他韦颗粒治疗能够更快地缓解患儿的临床症状,提高治疗效果,可在临床推广。
Objective:To study the effect of oseltamivir phosphate granules in the treatment of children with influenza.Methods:Ninety children with influenza-like illness were enrolled in our hospital.According to their admission time,they were randomly divided into the control group and the observation group.The control group was treated with ribavirin.The observation group was treated on the basis of control group and plus oseltamivir phosphate particles,clinical symptoms of remission time and adverse reactions after treatment,and patients’satisfaction were compared.Results:The effective rate of the treatment group was97.8%and84.4%in the observation group and the control group respectively.The effective rate of the treatment group was higher than that of the control group(P<0.05);adverse reaction between the control group and the observation group(P<0.05).The clinical symptom relief time of the observation group was shorter than that of the control group(P<0.05);the parents of the observation group had no significant difference(P>0.05)The satisfaction rate of treatment(95.6%)was higher than that of the control group(84.4%),P<0.05.Conclusion:The application of oseltamivir phosphate granules in children with influenza-like illness can relieve the clinical symptoms and improve the therapeutic effect in children.
作者
刘中梁
刘贤伟
LIU Zhong-liang;LIU Xian-wei(Lianxi District People's Hospital of Jiujiang City, Jiujiang Jiangxi 332005, China)
出处
《药品评价》
CAS
2017年第6期49-51,共3页
Drug Evaluation
作者简介
刘中梁，女，本科，临床医学，儿科主治医师，主要从事儿科疾病治疗工作。电话:0792-8251395；E-mail：307767521@qq.com
