不同的血液净化方式对维持性血液透析患者微炎症状态的影响被引量：2

Effect of different blood purification methods on the micro-inflammatory state of patients with maintenance hemodialysis

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摘要目的:探讨不同的血液净化方式对维持性血液透析患者微炎症状态的影响。方法:收治维持性血液透析患者60例,随机分成血液透析(HD)组、高通量血液透析(HDF)组和HD串联HDF(HD+HDF)组。HD组给予血液透析,HDF组给予高通量血液透析,HD+HDF组给予血液透析联合高通量血液透析,比较3组炎症因子水平。结果:3组治疗后IL-6、CRP、TNF-α明显下降(P<0.05)。治疗后,HD+HDF组IL-6、CRP、TNF-α下降幅度较大,优于HD组和HDF组(P<0.05)。结论:HD+HDF方式能够明显改善维持性血液透析患者的微炎症状态。 Objective:To investigate the effect of different blood purification methods on the micro-inflammation state of patientswith maintenance hemodialysis.Methods:60 cases of patients with maintenance hemodialysis were randomly divided intohemodialysis (HD) group,high-flux hemodialysis (HDF) group and HD series HDF (HD+HDF) group.HD group were treated withhemodialysis,HDF group were treated with high-flux hemodialysis,HD+HDF group were treated with hemodialysis combined withhigh-flux hemodialysis,and the levels of inflammatory factors of the 3 groups were compared.Results:The IL-6,CRP,TNF-a of the3 groups after treatment were decreased significantly(P<0.05).After treatment,the IL-6,CRP,TNF-a of HD + HDF groupdecreased more significantly, which was better than that of HD group and HDF group(P<0.05).Conclusion:HD + HDF couldimprove the micro-inflammatory state of patients with maintenance hemodialysis significantly.

作者张红群张侠 Zhang Hongqun;Zhang Xia(The People's Hospital of Yongcheng City,Henan Province 476600)

机构地区河南省永城市人民医院

出处《中国社区医师》 2016年第21期20-20,22,共2页 Chinese Community Doctors

关键词维持性血液透析血液灌流高通量血液透析微炎症状态 Maintenance hemodialysis Hemodialysis High-flux hemodialysis Micro-inflammatory state

分类号 R692.5 [医药卫生—泌尿科学]

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