摘要
针对目前国际上日渐重视银杏叶提取物及其制剂中烷基酚含量的情况 ,建立了一种简单的高效液相色谱 (HPLC)测定方法 ,该方法可分别测定银杏酸和白果酚的含量 ,灵敏度高 ,最小检出量低 ,回收率为98.83% ,相对标准偏差为 3.57% (n=5)。同时研究了能保证有效成分黄酮和内酯含量的银杏叶提取物脱银杏酸的方法。
A simple HPLC method for quantitative determination of alkylphenols,including ginkgolic acids and ginkgols,in Ginkgo biloba leaves,extracts and preparations was established.Relative standard deviation of the method is 3.57% ( n =5),and recovery is 98.83%.In order to decrease the content of ginkgolic acids in commercial GBE( G.biloba leaves extracts)products,a method of extracting alkylphenols from GBE was studied.A suitable mixed solvent A was developed to obtain GBE containing flavonoids 24%,terpene lactones 6%,and ginkgolic acids less than 10 mg/kg.
出处
《林产化学与工业》
EI
CAS
CSCD
2002年第3期6-10,共5页
Chemistry and Industry of Forest Products
基金
国家自然科学基金资助项目 ( 39870 6 15)
