摘要
目的观察下肢深静脉血栓介入治疗局部肝素化的治疗效果。方法选取本院收治的单侧下肢深静脉血栓患者30例,给予腘静脉介入导管溶栓治疗。经腘静脉置入溶栓导管和血管鞘,持续给予微量尿激酶和肝素,采溶栓导管及手臂静脉血检测凝血功能。结果患者不同时段全身与局部的活化部分凝血活酶值存在较大差异(P <0.05)。30日后随访患者疼痛以及肿胀均有显著好转。结论检测局部肝素化对治疗静脉血栓有显著的疗效,同时又可以降低抗凝并发症的发生率。
Objective To investigate the effect of local heparin therapy in interventional treatment of deep venous thrombosis of lower extremities. Methods 30 patients with unilateral deep venous thrombosis in our hospital were selected as the subjects of this study. The patients were treated with thrombolytic therapy with popliteal vein interventional catheter. Thrombolytic catheter and vascular sheath were inserted through popliteal vein. Microamounts of urokinase and heparin were given continuously. The thrombolytic catheter and arm venous blood were collected to test the coagulation function. Results There were significant differences between the whole body and local activated partial thromboplastin values at different time intervals(P<0.05). The pain and swelling of the patients were improved significantly after 30 days follow-up. Conclusion The detection of local heparin has a significant effect on the treatment of venous thrombosis,which could reduce the incidence of anticoagulant complications.
作者
郭巍巍
GUO Weiwei(Department of Interventional Medicine,Binhai People's Hospital,Yancheng,Jiangsu 224500,China)
出处
《大医生》
2018年第11期153-154,共2页
Doctor
关键词
下肢深静脉血栓
介入性溶栓
局部肝素化
deep venous thrombosis of lower extremity
interventional thrombolysis
local heparinilization
作者简介
郭巍巍,本科,主治医师,研究方向:下肢深静脉血栓介入术前后肝素化疗效评估。