摘要
目的观察瓣膜置换联合改良CoxⅢ迷宫术对风湿性心脏瓣膜病伴房颤患者的治疗效果。方法选取本院收治的风湿性心脏瓣膜病伴房颤患者的临床资料,根据其治疗方式分为对照组和观察组,对照组给予瓣膜置换术,观察组给予瓣膜置换联合改良CoxⅢ迷宫术。比较两组心功能、血压变异性、应激指标和不良反应发生率的差异。结果治疗后,观察组LAD、RAD、LVESD、LVEDD、皮质醇、IL-6和TNF-α水平均显著低于对照组(P<0.05);观察组SDNN、SDANN、RMSSD和PNN50水平均显著高于对照组(P<0.05);两组患者电解质紊乱、低血压和心脏骤停等不良事件发生率比较差异无统计学意义(P>0.05)。结论瓣膜置换联合改良CoxⅢ迷宫术对风心病瓣膜病伴房颤患者有较好的治疗效果,可明显改善患者的心功能,具有良好的应用价值。
Objective To observe the effect of valve replacement combined with modified Cox Ⅲ maze procedure AF patients with RHD of valvular heart disease with atrial therapeutic effect. Methods A retrospective analysis of the clinical data of rheumatic valvular heart disease with atrial fibrillation in our hospital,according to their treatment,divided into control group and observation group,The control group was given valve replacement,and the observation group was given valve replacement combined with improved Cox-Ⅲ maze. The differences of cardiac function,blood pressure variability,stress index and incidence of adverse events were compared between the two groups. Results After treatment,the levels of LAD,RAD,LVESD,LVEDD,cortisol,IL-6 and TNF-alpha in the observation group were lower than those in the control group(P<0.05).The levels of SS,SDANN,RMSSD and PN50 in the observation group were higher than those in the control group(P<0.05).There was no significant difference in the incidence of adverse events such as electrolyte disturbance,hypotension and cardiac arrest between the two groups. Meaning(P>0.05). Conclusion Valve replacement combined with modified Cox Ⅲ maze procedure fibrillation has a good curative effect on rheumatic valvular disease complicated with atrial disease,can improve heart function of patients,has good application value.
作者
陈辛亮
迟立群
梁林
肖巍
CHEN Xinliang;;CHI Liqun;LIANG Lin;XIAO Wei(Beijing Anzhen Hospital,Beijing 100029,China)
出处
《大医生》
2018年第7期17-19,共3页
Doctor
关键词
瓣膜置换
风湿性心脏病
房颤
血压变异性
应激
valve replacement
rheumatic heart disease
atrial fibrillation
blood pressure variability
stress
作者简介
陈辛亮,硕士,主治医师,研究方向:心血管疾病。
