摘要
目的探讨妊娠糖尿病采用胰岛素持续皮下输注治疗临床疗效及安全性分析。方法将2016年3月—2017年3月在该院治疗的60例妊娠糖尿病患者随机分为两组,对照组采用多次皮下注射胰岛素治疗,观察组采用胰岛素泵持续皮下输注胰岛素治疗,比较两组患者的血糖情况、孕妇并发症情况、胎儿并发症情况。结果观察组治疗后空腹血糖、餐后2?h血糖、Hb A1c与对照组相比无明显差异(P>0.05),观察组胰岛素用量明显低于对照组,差异有统计学意义(P<0.05);观察组孕妇羊水过多、妊高症、剖宫产、产后低血糖等并发症发生率明显低于对照组,差异有统计学意义(P<0.05);观察组胎儿并发巨大儿、早产儿、新生儿窒息、死胎等发生率明显低于对照组,差异有统计学意义(P<0.05)。结论妊娠糖尿病采用胰岛素持续皮下输注治疗效果确切,胰岛素用量减少,且血糖控制水平佳,孕妇及胎儿相关并发症发生率明显降低,具有积极的临床意义。
Objective To investigate the clinical efficacy and safety analysis of insulin sustained subcutaneous infusion in gestational diabetes.Methods From March 2016 to March 2017 in our hospital,60 patients with gestational diabetes mellitus were randomly divided into two groups:control group treated with multiple subcutaneous injections of insulin therapy,and observation group treated with insulin pump continuous subcutaneous insulin infusion.Level of blood sugar,complications of pregnant women and fetal complications were compared between groups.Results After treatment,2 h postprandial blood glucose,Hb A1 c and fasting glucose in the observation group showed no significant difference compared with the control group(P>0.05),the insulin dosage of the observation group was obviously lower than in the control group,the difference was statistically significant(P<0.05).The incidence of complications such as excessive amniotic fluid,ectopia,cesarean section and postpartum hypoglycemia was significantly lower in the observation group than in the control group,with statistically significant difference(P<0.05).The incidence of fetal complication,premature infant,neonatal asphyxia and stillbirth were significantly lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion The effect of gestational diabetes using continuous subcutaneous insulin infusion therapy is exact,with reducted insulin dosage ion and the blood sugar level control,and significantly lower incidence of related complications in pregnant women and fetus.
出处
《大医生》
2017年第5期18-19,21,共3页
Doctor
关键词
妊娠糖尿病
胰岛素
持续皮下输注治疗
疗效及安全性
gestational diabetes
Insulin
Continuous subcutaneous infusion therapy
Efficacy and safety
