摘要
为了解盐穗木提取物对金黄色葡萄球菌的抑菌效果,解决金黄色葡萄球菌耐药性的问题,笔者测定盐穗木乙醇提取物和正丁醇萃取物的抑菌圈直径、最低抑菌浓度(MIC)、最低杀菌浓度(MBC)及生长曲线。结果表明,盐穗木正丁醇萃取物的抑菌活性显著高于乙醇提取物,盐穗木乙醇提取物和盐穗木正丁醇萃取物的MIC分别为150.00 mg/mL和25.00 mg/mL,MBC分别为250.00 mg/mL和50.00 mg/mL。说明盐穗木正丁醇萃取物有良好的抑菌效果,可为新型抗菌药物的研发奠定基础。
In order to understand the antibacterial activities of Halostachys caspica on Staphylococcus aureus and solve the problem of drug resistance of Staphylococcus aureus.The antibacterial activities of ethanol extract and N-butanol extract from Halostachys Caspica on Staphylococcus aureus was studied by measuring the inhibition zone diameter,minimal inhibitory concentration(MIC),minimum bactericidal concentration(MBC)and growth curve.The results showed that the antibacterial activity of N-butanol extract was significantly higher than that of ethanol extract.The MIC of ethanol extract and N-butanol extract were 150.00 mg/mL,25.00 mg/mL,and the MBC were 250.00 mg/mL,50.00 mg/mL,respectively.The results showed that the extract of N-butanol from Halostachys Caspica had better antibacterial activities and could lay a foundation for the development of novel antibacterial agents.
作者
银亚博
陶大勇
王硕
刘强
邹抒洁
YIN Ya-bo;TAO Da-yong;WANG Shuo;LIU Qiang;ZOU Shu-jie
出处
《当代畜牧》
2019年第7期29-32,共4页
Contemporary Animal Husbandry
基金
国家自然科学基金项目(31560711):盐穗木正丁醇提取物及目标单体对St.aureus细胞壁作用机制研究
塔里木大学大学生创新创业训练项目(2017013):盐穗木生物碱正丁醇萃取物对金黄色葡萄球菌细胞壁成分影响分析
研究生科研创新项目(TDGKI201713):盐穗木正丁醇萃取物抑菌单体化合物的研究
自治区研究生科研创新项目(XJGRI 2017128)
关键词
盐穗木提取物
金黄色葡萄球菌
最低抑菌浓度
最低杀菌浓度
Halostachys caspica
Staphylococcus aureus
minimal inhibitory concentration
minimum bactericidal concentration
作者简介
第一作者简介:银亚博,1995年出生,女,汉族,河南省遂平县人,塔里木大学本科生;通讯作者:陶大勇,1967年出生,男,河南省罗山县人,教授,硕士生导师,博士研究生,研究方向为临床兽医学及中草药学。
