摘要
Objective:To assess the 10-year incidence of retinal vein occlusion(RVO)and its predictors in an older population.Methods:The Blue Mountains Eye Study examined 3654 residents aged 49 years and older(82.4% response)from 1992 to 1994,reexamined 2335 residents(75.1% of survivors)from 1997 to 1999,and reexamined 1952 residents(75.6% of survivors)from 2002 to 2004.Incident RVO was assessed from stereoscopic retinal photographs.Kaplan-Meier cumulative 10-year incidence was calculated.Results:After excluding 47 residents with RVO at baseline and 171 residents with no photographs at either followup examination,2346 residents were considered at risk of developing RVO.The cumulative 10-year incidence of RVO was 1.6%.Age was significantly associated with the incidence of RVO(P=.03,Mantel-Haenszel χ 2 test for trend).Factors predicting the incidence of RVO included mean arterial blood pressure(age-adjusted odds ratio OR,1.41 per 10-mm Hg increase),ocular perfusion pressure(OR,1.71 per 10-mm Hg increase),obesity(OR,2.16),and presence of retinal arteriolar wall signs(focal narrowing:OR,3.37;arteriovenous nicking:OR,4.09;and opacification:OR,4.89).Conclusions:Older age(≥ 70 years),increasing mean arterial blood pressure,and atherosclerotic retinal vessel signs were significant predictors of incident RVO.
Objective:To assess the 10-year incidence of retinal vein occlusion(RVO)and its predictors in an older population.Methods:The Blue Mountains Eye Study examined 3654 residents aged 49 years and older(82.4% response)from 1992 to 1994,reexamined 2335 residents(75.1% of survivors)from 1997 to 1999,and reexamined 1952 residents(75.6% of survivors)from 2002 to 2004.Incident RVO was assessed from stereoscopic retinal photographs.Kaplan-Meier cumulative 10-year incidence was calculated.Results:After excluding 47 residents with RVO at baseline and 171 residents with no photographs at either followup examination,2346 residents were considered at risk of developing RVO.The cumulative 10-year incidence of RVO was 1.6%.Age was significantly associated with the incidence of RVO(P=.03,Mantel-Haenszel χ 2 test for trend).Factors predicting the incidence of RVO included mean arterial blood pressure(age-adjusted odds ratio OR,1.41 per 10-mm Hg increase),ocular perfusion pressure(OR,1.71 per 10-mm Hg increase),obesity(OR,2.16),and presence of retinal arteriolar wall signs(focal narrowing:OR,3.37;arteriovenous nicking:OR,4.09;and opacification:OR,4.89).Conclusions:Older age(≥ 70 years),increasing mean arterial blood pressure,and atherosclerotic retinal vessel signs were significant predictors of incident RVO.
出处
《世界核心医学期刊文摘（眼科学分册）》
2006年第10期14-14,共1页
Digest of the World Core Medical Journals:Ophthalmology
