摘要
To investigate the frequency and the features of contact sensitization to prop olis in children, we patch tested 1255 consecutive children suspected of allergi c contact dermatitis with propolis 20%petrolatum over an 8-year period (1995- 2002). Positive responses were observed in 5.9%of patch-tested subjects, with a significantly higher frequency in boys than in girls. The dermatitis was local ized mainly on the face, hands and limbs. A significant linear increase in the a nnual frequency of propolis allergy was noted. Confirming literature data, a sig nificant association with balsam of Peru sensitivity was present in children rea cting to propolis, linked to the presence of common constituents in the 2 substa nces. In conclusion, based on our data, we suggest that propolis should not be u sed in topical products for children because of its high sensitization rate at t he paediatric age.
To investigate the frequency and the features of contact sensitization to prop olis in children, we patch tested 1255 consecutive children suspected of allergi c contact dermatitis with propolis 20%petrolatum over an 8-year period (1995- 2002). Positive responses were observed in 5.9%of patch-tested subjects, with a significantly higher frequency in boys than in girls. The dermatitis was local ized mainly on the face, hands and limbs. A significant linear increase in the a nnual frequency of propolis allergy was noted. Confirming literature data, a sig nificant association with balsam of Peru sensitivity was present in children rea cting to propolis, linked to the presence of common constituents in the 2 substa nces. In conclusion, based on our data, we suggest that propolis should not be u sed in topical products for children because of its high sensitization rate at t he paediatric age.
