摘要
Oddi括约肌功能障碍(sphincterofoddidysfunction,SOD)是指Oddi括约肌失去正常生理功能,出现上腹部胆胰源性疼痛、餐后腹胀、肝或胰酶升高、胆总管扩张或胰腺炎发作等的临床综合征,多见于胆囊切除术后患者.尽管诊断和治疗该疾病的既定标准已应用于临床,但SOD作为一个疾病过程本身,其诊断方法和治疗手段一直都存在争议,部分原因是它的自然病程,疾病治疗过程及治疗结果在长期随访的大型对照研究中尚未明确证实,存在很多困惑.本文就近年来相关领域所取得的最新研究进展进行简要综述,旨在全面分析目前胆囊切除术后SOD的诊断治疗现状与存在的问题,并为医生诊断和治疗该疾病提供适当的建议.
Sphincter of Oddi dysfunction （SOD） is a clinical syndrome referring to the loss of normal physiologicalfunction of the sphincter of Oddi with upper abdominalpain from the gallbladder and pancreas, postprandialabdominal bloating, elevation of liver or pancreaticenzymes, common bile duct dilation, pancreatitisand so on. SOD is more common in patients aftercholecystectomy. Although the established criteria fordiagnosing and treating SOD have been applied inclinical practice, its diagnosis and treatment have longbeen a controversial topic since the best diagnostic andtreatment methods are still unconfirmed, partly becauseof its natural course, disease treatment process, and longtermfollow-up outcomes that have not been determinedin large controlled studies. This article briefly reviews thelatest research of SOD and comprehensively analyzes thecurrent status and existing problems in the diagnosis andtreatment of SOD, with an aim to provide appropriateadvice for clinicians to diagnose and treat this disease.
作者
杨迎
王凯
王长淼
Ying Yang;Kai Wang;Chang-Miao Wang(Department of General Surgery,the First Affiliated Hospital of Dalian MedicalUniversity,Dalian 116011,Liaoning Province,China)
出处
《世界华人消化杂志》
CAS
2018年第30期1735-1741,共7页
World Chinese Journal of Digestology
基金
国家自然科学基金资助项目
No.81774082~~
作者简介
杨迎,研究生,主要从事胆道动力的研究.;通讯作者：王长淼,教授,116011,辽宁省大连市西岗区中山路222号,大连医科大学附属第一医院普外科.wangchangmiaodl@sohu.com
