摘要
Omega-3脂肪酸磷脂生理功能明确,生物利用度高,在医药、保健品领域具有巨大的市场潜力,其制备方法是全球磷脂研究开发的新动向。综述了目前Omega-3脂肪酸磷脂的制备方法,包括天然提取法、酶促转化法、化学合成法及微生物发酵法。天然提取法是最早获得Omega-3脂肪酸磷脂产品的方法,主要包括溶剂萃取法、膜分离法、柱层析法和盐沉淀法;酶促转化法主要包括酶促酯交换法和酶促酯化法,是目前Omega-3脂肪酸磷脂合成效率最高、最常用的方法;化学合成法及微生物发酵法处于初步研究阶段,为Omega-3脂肪酸磷脂的制备提供了新的思路。
Omega -3 fatty acids phospholipids have clear physiological function and high bioavailability, its market potential is huge in the fields of medicine and nutritional products, and more and more resear- ches are focusing on the preparation methods of Omega -3 fatty acids phospholipids. The preparation methods of Omega -3 fatty acids phospholipids were reviewed, including natural extraction, enzymatic catalysis conversion, chemical synthesis and microbial fermentation. Omega -3 fatty acids phospholipids products were firstly prepared by natural extraction method, including solvent extraction, membrane sepa- ration, column chromatography and salt precipitation. Enzymatic catalysis conversion was the most com- mon method with the highest efficiency currently, including enzymatic transesterification and enzymatic esterification. Chemical synthesis and microbial fermentation provided new preparation ways to obtain Omega -3 fatty acids phospholipids which were in preliminary study stage and required further research.
作者
王俊
王淑娜
许新德
彭永健
WANG Jun;WANG Shuna;XU Xinde;PENG Yongjian(Xinchang Pharmaceutical Factory,Zhejiang Medicine Co,Ltd,Xinchang 312500,Zhejiang,China)
出处
《中国油脂》
CAS
CSCD
北大核心
2018年第8期47-51,共5页
China Oils and Fats
作者简介
王俊（1990-），男，助理工程师，研究方向为化工医药生产及过程装备控制（E-mail）wangj@xcpharma.com。;通信作者：彭永健，工程师（E-mail）pengyj@xcpharma．com。
