摘要
目的了解本市孕前男性精液质量现状及其影响因素,为孕前夫妇优生指导提供参考。方法对401例孕前男性进行体格检查和病史询问,填写健康调查表,并进行精液质量检测。结果 (1)孕前男性的精液量、精子浓度的中位数分别为3.0m L、71.7×106/m L;前向运动精子(PR)、精子总活力、存活率中位数分别是36.3%、46.5%、49.1%;精子形态正常率、精子DNA碎片指数正常率的中位数分别为3.1%,90.92%。(2)与WHO第五版标准对比:90%的孕前男性精液量、精子浓度和精子总数、精浆锌含量、精浆果糖含量正常;但精子PR,总活力和存活力、形态的正常率较低,符合率分别是53.8%,63.7%;63.7%、54.9%。(3)多因素关联性分析发现:吸烟、饮酒、经常热水浴和生活压力显著影响精子质量,差异具统计学意义(P<0.05)。结论重庆市孕前男性精液质量较差,主要表现在精子活力下降和形态畸形。改变吸烟、饮酒、热水浴等不良生活习惯和减轻生活压力对提高男性精子质量非常重要。
Objective To investigate semen quality and its influencing factors of preconception males in Chongqing so as to provide reference for good prenatal and postnatal care of preconception couples. Methods Total of 401 preconception males were recruited in the study for physical examination, medical history inquiry, filling in a health questionnaire, and semen quality analysis. Results（1） The median of semen volume and sperm concentration was 3.0 ml、71.7＊106/ml, respectively. The median rate of sperm survival and sperm activity was 36.3%, 46.5%; the median rate of normal sperm morphology and sperm DNA was 3.1%, 90.92%.（2） According to the standard of WHO5： semen volume, sperm concentration, sperm count, zinc content and fructose were all normal for 90% preconception males; but sperm activity rate and survival rate and normal morphology were lower（53.8%, 63.7%, 54.9%）.（3） Correlation analysis of multiple factors showed that smoking, drinking, hot water bath and life stress affected the quality of sperm significantly（P〈0.05）. Conclusion Semen quality of preconception males is poor in Chongqing, such as sperm motility decrease and morphologic malformation. It is very important to improve the sperm quality of preconception male by changing the bad habits of smoking, drinking, hot water bath and reducing the pressure of life.
作者
包华琼
孙岚
杨学妞
丁杰
马世原
杨柳
徐小鸥
Bao Huaqiong;Sun Lan;Yang Xueniu;Ding Jie;Ma Shiyuan;Yang Liu;Xu Xiaoou(Affiliated Hospital of Chongqing Institute for Population and Family Planning,Chongqing Key Laboratory of Birth Defects and Reproductive Health,Chongqing 400020,China)
出处
《中国男科学杂志》
CAS
CSCD
2018年第3期41-46,共6页
Chinese Journal of Andrology
基金
重庆市基本科研业务费项目(2016cstc-jbky-01722)
作者简介
共同第一作者/通讯作者:包华琼,E-mail:baohuaqiong@163.com;共同第一作者:孙岚
