摘要
目的观察冠心病心力衰竭患者施予曲美他嗪与琥珀酸美托洛尔联合治疗的效果。方法将本院收治的120例冠心病心力衰竭患者随机分为A组与B组,各60例。A组行常规治疗,B组在A组基础上施予曲美他嗪与琥珀酸美托洛尔联合治疗,比较两组的临床疗效及治疗前后患者的心肌功能情况。结果治疗后B组患者LVEDD、LVESD、DBF、SBF低于A组,LVEF高于A组,差异有统计学意义(P<0.05);A组总有效率为81.67%,低于B组的96.67%,差异有统计学意义(P<0.05)。结论曲美他嗪与琥珀酸美托洛尔联合治疗冠心病心力衰竭,临床效果显著,可有效改善患者心肌功能。
Objective To observe the effect of combined treatment with trimetazidine and metoprolol succinate in patients with coronary heart disease and heart failure.Methods 120 patients with coronary heart disease admitted to our hospital were randomly divided into group A and group B,60 cases in each group.Group A was treated routinely.Group B was treated with combination of trimetazidine and metoprolol succinate on the basis of group A.The clinical efficacy of the two groups and the myocardial function of the patients before and after treatment were compared.Results After treatment,LVEDD,LVESD,DBF and SBF were lower in group B than in group A,and LVEF was higher than that in A group,the difference was statistically significant（ P〈0.05）,and the total effective rate of group A was 81.67%,lower than that of group B 96.67%,and the difference was statistically significant（ P〈0.05）.Conclusion Trimetazidine combined with metoprolol succinate is effective in treating coronary heart disease with heart failure.It can effectively improve myocardial function in patients with coronary heart disease.
作者
何玲玲
程淑芬
HE Ling-ling;CHENG Shu-fen(Department of Internal Medicine,Subject Four,the 452 Hospital of PLA,Chengdu 610021,Sichuan,China)
出处
《医学信息》
2018年第13期142-143,共2页
Journal of Medical Information
关键词
冠心病
心力衰竭
曲美他嗪
琥珀酸美托洛尔
Coronary heart disease
Heart failure
Trimetazidine
Metoprolol succinate
作者简介
何玲玲（1973．7-），女，四川绵阳人，硕士，主治医师，研究方向：心血管内科疾病的诊治
