摘要
目的探讨肺心病急性加重期患者应用依那普利与丹参酮联合治疗的临床疗效。方法选取该院2014年12月—2016年6月期间该院收治的102例肺心病急性加重期患者作为该次研究病例,按照治疗方式的不同将其分为对照组和研究组,各51例,对照组应用常规的治疗方式,并在此基础上加用依那普利治疗,研究组在对照组基础上加用丹参酮治疗,对比分析两组患者的临床效果。结果研究组的总有效率为94.11%,显著高于对照组(76.47%),差异有统计学意义(χ~2=6.331 0,P<0.05)。且研究组患者治疗后的血气PaCO_2(47.34±9.11)mmHg以及血液流变学[全血粘度(1.51±1.17)mPa·s和心功能指标CO(4.70±0.82)L/min明显优于对照组(t=5.221 4、2.051 1、3.273 6,P<0.05),同时研究组患者治疗后的各项指标也显著优于对照组,两组差异有统计学意义(P<0.05)。结论依那普利与丹参酮联合治疗肺心病急性加重期患者的临床效果明显,值得临床推广应用。
Objective This paper tries to investigate the clinical efficacy of enalapril combined with tanshinone in patients with acute exacerbation of pulmonary heart disease. Methods A total of 102 patients with acute exacerbation of pulmonary heart disease admitted to the hospital from December 2014 to June 2016 were selected as the study cases and divided into control group and study group according to the different treatment methods. In the control group, conventional treatment was used. On the basis of this, enalapril treatment was added. The study group was given tanshinone on the basis of the control group, and the clinical effect was compared between the two groups. Results The total effective rate of the study group was 94.11%, which was significantly higher than that of the control group 76.47%, The difference was statistically significant（cm^2=6.331 0,P〈0.05）.The study of PaCO2 blood groups after treatment（47.34±9.11） mmHg] and blood rheology of blood viscosity（1.51±1.17） mPa·s and heart function index of [CO（4.70±0.82）L/min]was significantly better than the control group,The difference was statistically significant（t=5.221 4, 2.051 1, 3.2736,P〈0.05）, at the same time, the study on the index group after treatment was significantly better than the control group,the two groups have significant difference, which was statistically significant（P〈0.05）. Conclusion Enalapril combined with tanshinone in patients with acute exacerbation of pulmonary heart disease clinical effect is obvious,it is worth promoting the clinical application.
作者
张盼盼
ZHANG Pan-pan(Ancillary Intravenous Drug Deployment Center,Capital Medical University,Beijing Province,100029 China)
出处
《系统医学》
2018年第3期135-137,共3页
Systems Medicine
关键词
依那普利
丹参酮
肺心病
急性加重期
Enalapril
Tanshinone
Pulmonary heart disease
Acute exacerbation
作者简介
张盼盼（1989-），女，本科，药师初级。
