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微小乳腺癌患者应用乳腺钼靶诊断效果及对患者近期有效率、远期生存率的影响 被引量:7

Diagnostic Effect of Mammography in Patients with Small Breast Cancer and Its Effect on Shortterm Effective Rate and Long-term Survival Rate
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摘要 目的:探讨微小乳腺癌患者采用乳腺钼靶诊断效果及对患者近期有效率、远期生存率的影响。方法:选择2012年12月-2014年12月入院治疗的微小乳腺癌患者200例,所有患者均经过手术病理检查最终得到确诊;手术前患者均行乳腺钼靶X线检查,将乳腺钼靶X线检查结果与手术病理结果进行比较;对于确诊的微小乳腺癌患者行单纯乳腺切除+腋窝淋巴结清扫术治疗,术后患者采用TAC(多西他赛+表阿霉素+环磷酰胺)化疗方案治疗,对患者进行3周期化疗,治疗后对患者进行3年随访,分析微小乳腺癌患者采用乳腺钼靶诊断效果及对患者近期有效率、远期生存率的影响。结果:200例微小乳腺癌患者均经过手术病理检查最终确诊,乳腺钼靶X线下最终确诊196例,确诊率为96.00%,与手术病理结果比较,差异无统计学意义(P>0.05);确诊的196例患者中良性钙化23例,占11.73%;173例恶性钙化,占88.27%。良性钙化患者X线下主要表现为肿块存在块影,边界光滑、高密度,占8.16%;恶性钙化乳腺钼靶诊断表现为伴有肿块影,不规则或分叶状,占78.06%;经手术病理确诊的200例患者均行手术及术后化疗治疗,患者均顺利完成治疗,患者近期有效率为93.00%;微小乳腺癌患者治疗后对患者进行3年随访,患者1年生存率高于3年(P<0.05)。结论:微小乳腺癌患者采用乳腺钼靶诊断有助于提高临床确诊率,且与手术病理具有较高的诊断符合率;对于确诊微小乳腺癌患者采用单纯乳腺切除+腋窝淋巴结清扫术及术后化疗治疗有助于提高近期疗效及远期生存率,值得推广应用。 Objective:To investigate the micro breast cancer patients with breast mammography in the diagnosis of patients with recent effect and efficiency,affecting the long-term survival rate.Method:200 patients with small breast cancer in our hospital from December 2012 to December 2014 were selected,all patients were finally diagnosed by surgery and pathological examination before surgery;patients underwent mammography the results of X-ray examination,breast X-ray mammography and pathology results were compared;for small breast cancer patients with simple mastectomy plus axillary lymph node dissection,postoperative using TAC(Docetax el+Epirubicin+Cyclophosphamide),the patients were followed up for 3 years after three cycles of chemotherapy.The diagnostic effect of mammography and the effect on the short-term effective rate and long-term survival rate of patients with small breast cancer were analyzed.Result:All the 200 cases of small breast cancer were confirmed by operation and pathology,196 cases were diagnosed under mammography,the diagnostic rate was 96.00%,there was no significant difference between the results of operation and pathology(P〈0.05);of 196 patients,23 were benign calcification,accounting for 11.73%;there were 173 cases of malignant calcification,accounting for 88.27%.Patients with benign calcification under X-ray in order to present the mass,the margin was smooth and the density was high,accounting for 8.16%.The malignant calcification mammography was diagnosed as accompanied by mass shadow,irregular or lobular shape,accounting for 78.06%.200 patients confirmed by surgery and pathology are all treated with surgery and postoperative chemotherapy,all the patients completed the treatment successfully,the short-term effective rate was 93.00%.The patients with small breast cancer were followed up for 3 years,the 1-year survival rate was higher than that in 3 years(P〈0.05).Conclusion:Mammography diagnosis in patients with small breast cancer is helpful to improve the rate of clinical diagnosis and has a higher diagnostic rate with surgery and pathology. Simple axillary lymph node dissection and postoperative chemotherapy are helpful to improve the short term curative effect and long term survival rate of patients with small breast cancer,which is worth popularizing.
作者 张俊萍 ZHANG Junping(Zhuhai Maternal and Child Health Hospital,Zhuhai519000,China)
出处 《中国医学创新》 CAS 2018年第14期91-94,共4页 Medical Innovation of China
关键词 微小乳腺癌 乳腺钼靶 近期有效率 远期生存率 乳腺切除 腋窝淋巴结清扫术 Small breast cancer Mammography Short-term efficiency Long-term survival Masteetomy Axillary lymph node dissection
作者简介 通信作者:张俊萍
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