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SDF-1/CXCR4及HIF-1α在支气管哮喘气道重塑中的研究进展 被引量:1

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摘要 支气管哮喘发病过程较为复杂,涉及到T淋巴细胞、嗜酸性粒细胞、肥大细胞、中性粒细胞、气道上皮细胞等及多种细胞及细胞组分的参与,慢性炎症的长期刺激导致气道高反应性,使气道进一步痉挛狭窄,加剧通换气障碍、气流受限,这是哮喘发病、恶化和持续存在的关键环节。
出处 《浙江临床医学》 2018年第7期1324-1326,共3页 Zhejiang Clinical Medical Journal
基金 杭州市卫生科技计划项目(Y201764849)
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