摘要
目的评价青海省2017年手足口病网络实验室的运转情况。方法分析青海省2017年手足口病网络实验室病毒学监测数据，评价青海省手足口病网络实验室运转情况。
结果2017年青海省各网络实验室共检测病例标本574份，病毒核酸检测阳性368份，阳性率为64.11%。病毒分离获得121株阳性毒株，经基因序列测定和分析，100株EV71基因型别均为C4a，16株CA16基因型别均为B1b，5株为其他肠道病毒。2017年青海省级手足口病网络实验室均通过了国家级手足口病实验室年度核酸盲样考核及现场认证。结论青海省手足口病实验网络运转良好，为青海省手足口病监测提供实验技术支撑。
ObjectiveTo evaluate the running status of Qinghai provincial hand foot and mouth disease （HFMD） laboratory network in 2017.MethodsThe surveillance database developed in Qinghai provincial HFMD laboratory network in 2017 were analyzed, and the indicators for the running status of HFMD laboratory network in Qinghai province were evaluated.ResultsIt was shown that 574 samples of suspected HFMD cases were detected by real time RT-PCR in 2017, and 368 were positive, the positive rate was 64.11%. Then 121 virus strains were isolated, the results of sequencing and analysis showed that 100 strains were EV71 with C4a genotype, 16 strains were CA16 with B1b genotype, and 5 strains belonged to the other enterovirus. In addition, Qinghai provincial HFMD network labs passed all the confirmatory test and proficiency test, and on-site review held by national HFMD laboratory in 2017, respectively.ConclusionsQinghai provincial HFMD laboratory network has been established and running well. It provided important scientific basis for HFMD surveillance in Qinghai province.
作者
范丽霞
巴卓玛
李崇亥
姜双应
赵生仓
严冬梅
冀天娇
Fan Lixia;Ba Zhuoma;Li Chonghai;Jiang Shuangying;Zhao Shengcang;Yan Dongmei;Ji Tianjiao(Qinghai Center for Disease Control and Prevention, Xining 810007, China;National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China)
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
2018年第3期286-288,共3页
Chinese Journal of Experimental and Clinical Virology
基金
国家科技重大传染病监测技术平台项目（2012ZX10004-208）
关键词
手足口病
肠道病毒
基因型
Hand
foot and mouth disease
Enterovirus
Genotype
作者简介
通信作者：赵生仓，Email：601877664@qq．com
