摘要
中药毒性成分是造成中药不良反应的重要原因之一。选择马兜铃酸作为中药毒性成分代表,检索了含马兜铃酸发明专利申请文献,对上述专利技术现状进行了梳理,以期为中药毒性成分的研究开发提供参考,达到减少中药不良反应发生的目的,保障临床用药安全。
The toxic components is one of the important causes of adverse reactions of TCM. Aristolochic acid as a typical representative of the toxic components of TCM, we searched and combed more than a hundred patent applications about aristolochic acid, analyzed and researched above patent technology, obtain some enlightenments, which may provide reference for the research and development of toxic components of TCM and to reduce the occurrence of adverse reactions of TCM, so as to ensure the safety of clinical medication.
作者
杨媛
YANG Yuan(State Intellectual Property Office of the PRC, Beijing 100088, China)
出处
《药物评价研究》
CAS
2018年第5期748-752,共5页
Drug Evaluation Research
关键词
马兜铃酸
发明专利
中药毒性
不良反应
aristolochic acid
patent
toxicity components of traditional Chinese medicine
adverse reaction
作者简介
杨嫒（1983-），女，硕士研究生，主任科员，工作领域：中药专利审查。E-mail：yangyuan@sipo．gov．cn
